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Line Insertion through a Long Umbilical Stump: A Concept Generating Laboratory Study.

Itamar Nitzan1,2, Yshia Langer2,3, Yair Kasirer1,2

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American Journal of Perinatology
|August 4, 2025
PubMed
Summary
This summary is machine-generated.

Umbilical vein catheterization can be advanced 10-20 cm in umbilical cord segments, potentially reducing discomfort for preterm infants during line insertion. Further clinical studies are needed to confirm this minimal handling approach.

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Area of Science:

  • Neonatal medicine
  • Medical device engineering
  • Pediatric surgery

Background:

  • Umbilical line insertion is a common but uncomfortable procedure for preterm infants.
  • Minimizing handling during neonatal procedures is crucial for infant well-being.

Purpose of the Study:

  • To investigate the feasibility of catheterizing a long segment (10-20 cm) of the umbilical vein.
  • To develop a method for umbilical vein catheterization that minimizes infant discomfort.

Main Methods:

  • Laboratory proof-of-concept study using ex vivo umbilical cord segments.
  • Phase 1: Exploration of techniques for long-segment umbilical vein catheterization.
  • Phase 2: Assessment of catheter advancement success rate using the optimized method.

Main Results:

  • Catheters were successfully advanced an average of 15.7 cm in 7 out of 10 umbilical cord segments.
  • Demonstrated the possibility of advancing a catheter within the umbilical vein through a long cord segment.

Conclusions:

  • Advancing a catheter within the umbilical vein through a long umbilical cord segment is achievable.
  • The proposed technique shows potential for a minimal handling approach to umbilical catheterization.
  • Clinical evaluation is necessary to validate the efficacy and safety of this method in neonates.