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Top 10 priorities for chronic cough: Canadian James Lind Alliance Priority-Setting Partnership (CAN-COUGH)
Saif Samari1,2, Ana Oliveira3,4,5,2, Danica Brister6
1Department of Medicine, McMaster University, Hamilton, ON, Canada.
ERJ Open Research
|August 5, 2025
Summary
This study identified key research and education priorities for chronic cough in Canada. Top needs include better treatments, improved diagnostics, and enhanced public awareness to improve patient care.
Area of Science:
- Pulmonology and Respiratory Medicine
- Health Services Research
- Patient-Centered Outcomes Research
Background:
- Chronic cough severely affects quality of life and presents treatment challenges.
- Limited effective treatments and access to interventions complicate management.
- Understanding patient and provider priorities is crucial for advancing chronic cough care.
Purpose of the Study:
- To identify and prioritize key areas for research, education, and knowledge dissemination for chronic cough in Canada.
- To establish a consensus on the most pressing needs from the perspectives of individuals with chronic cough and healthcare providers.
- To guide future initiatives aimed at improving the management and outcomes of chronic cough.
Main Methods:
- A cross-sectional study utilizing the James Lind Alliance (JLA) methodology.
- Online survey distributed to individuals with chronic cough and healthcare providers to rate priorities.
- A face-to-face Priority-Setting Partnership involving patient partners and a multidisciplinary working group to finalize a "Top 10" list.
Main Results:
- 74 individuals with chronic cough and 62 healthcare providers participated.
- Top priorities included enhancing knowledge of existing treatments, developing novel therapies, and improving diagnostic accuracy.
- The "Top 10" list emphasized infrastructure for treatment evaluation, understanding disease mechanisms, and public/policymaker awareness.
Conclusions:
- This is the inaugural priority-setting project for chronic cough, establishing critical research and education targets.
- The identified priorities provide a foundational roadmap for future interventions in chronic cough management.
- Addressing these priorities is essential for improving the care and quality of life for individuals experiencing chronic cough.
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