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Updated: Sep 12, 2025

Minimal Invasive Resection of Large Retrosternal Thyroid Goiter
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[Cardiac arrest secondary to thyroid storm].

David Napolitano1, Vinciane Corman2, Xavier Bertrand1

  • 1Service des Urgences, CHR Citadelle, Liège, Belgique.

Revue Medicale De Liege
|August 5, 2025
PubMed
Summary

Thyroid storm is a severe thyrotoxicosis complication. Early diagnosis and treatment with antithyroid drugs, beta-blockers, and glucocorticoids are crucial for managing this life-threatening condition.

Keywords:
Cardiac arrestHyperthyroidismThyroid storm

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Area of Science:

  • Endocrinology
  • Internal Medicine
  • Critical Care Medicine

Background:

  • Thyroid storm is a rare, life-threatening exacerbation of thyrotoxicosis.
  • It can be triggered by various factors including Graves' disease, toxic goiter, amiodarone, or trauma.

Observation:

  • Clinical manifestations are diverse, with cardiovascular complications being the most critical, potentially leading to cardio-respiratory arrest.
  • Diagnosis is often challenging, leading to delayed management.

Findings:

  • Treatment involves symptomatic management, antithyroid drugs, beta-blockers, and glucocorticoids to inhibit T4 to T3 conversion.
  • Thyroid surgery, radioactive iodine therapy, and extracorporeal membrane oxygenation (ECMO) are also therapeutic options.

Implications:

  • Prompt recognition of thyroid storm in hyperthyroid patients is essential.
  • Multifaceted treatment strategies are required to improve patient outcomes in this critical condition.