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Updated: Sep 12, 2025

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Published on: January 31, 2025
A Patient-Focused Comparative Analysis of Large Language Models for Epidural Analgesia Education
Akshar P Patel1, Stanley Joseph1, Ashna Bhardwaj1
1From the Medical College of Georgia, Augusta University, Augusta, Georgia.
Abstract:
Epidural analgesia is a common labor pain management method, yet patients often require clear education on its risks and benefits. This study assessed 2 large language models (LLM), ChatGPT (OpenAI) and MediSearch (Create.ai), as potential tools for educating patients about epidural analgesia. Using 100 patient-focused questions categorized by the Rothwell System, responses were evaluated with DISCERN reliability scores and readability metrics (Flesch-Kincaid Grade Level, Coleman-Liau Index). MediSearch achieved higher reliability (P < .0001), while ChatGPT excelled in readability (P =.0013). Findings highlight an imbalance between reliability and readability between the 2 LLMs.
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