Multisystem Langerhans cell histiocytosis with gastrointestinal involvement in an infant: A case report

Langerhans cell histiocytosis is a rare disease characterized by the accumulation of Langerhans cells, which are myeloid dendritic cells, associated with significant inflammation and varied systemic involvement. Gastrointestinal involvement is rare, preceded in more than 80% of cases by skin lesions. We report the case of a 5-month-old girl whose clinical presentation was skin lesions and proctorrhagia. A transdisciplinary approach allowed us to reach a diagnosis and initiate timely treatment.