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Comparison of the Corneal High-Order Aberration and Relative Corneal Refractive Power Distribution Induced by
Riping Zhang1, Youming Zhou, Yunxuan Ou
1Joint Shantou International Eye Center of Shantou University and the Chinese (R.Z., Y.Z., Y.O., J.L., M.Z.), University of Hong Kong, Shantou, China; Chinese University of Hong Kong Eye Centre (M.P.C.), Kowloon, China; and University of Pittsburgh School of Medicine (V.J.), Pittsburgh, PA.
Purpose:
This study compared the myopia control effects of corneal high-order aberrations (CHOA) from two orthokeratology (OK) lenses based on their relative corneal refractive power shifts.
Methods:
In this prospective cohort study, 101 school children with low to moderate myopia were divided into three groups: group A (N=35) used 3-curve design lenses, group B (N=31) used 4-curve design lenses, and group C (N=35) wore regular spectacles. Cycloplegic refraction, visual acuity, and axial length (AL) were measured at baseline and after one year. Keratometry and CHOA were assessed before and after 3 months of lens wear. Relative corneal refractive power shifts and summed corneal power change (SCPC) were calculated. One-way ANOVA and planned comparison analyzed group differences.
Results:
Group B showed significantly slower AL elongation than group A ( P =0.017) after OK treatment. Group B's SCPC was significantly higher than group A's ( P ≤0.005). Group B had a significant increase in horizontal coma ( P =0.004). Increased SCPC led to more coma aberration with four-curve lens wear ( P <0.01).
Conclusions:
The four-curve lens design was more effective in slowing AL elongation for OK treatment. It also caused significantly higher horizontal coma aberration than the three-curve design.
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