Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Clostridium difficile colitis in leukemia patients.

G Panichi, A Pantosti, G Gentile

    European Journal of Cancer & Clinical Oncology
    |October 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The role of germline mutations in non-small cell lung cancer: A systematic review of emerging genetic drivers and clinical implications.

    Critical reviews in oncology/hematology·2026
    Same author

    20th anniversary of adjuvant trastuzumab: reflections on a breakthrough moment.

    Annals of oncology : official journal of the European Society for Medical Oncology·2025
    Same author

    Managing relapses during or after adjuvant CDK4/6 inhibitors in HR-positive/HER2-negative early breast cancer: an emerging challenge.

    ESMO open·2025
    Same author

    Effective and safe use of alirocumab in spinal and bulbar muscular atrophy with high cardiovascular risk: a case report.

    European review for medical and pharmacological sciences·2025
    Same author

    Care pathway of asylum seekers in the health care access points following inclusion in the PREMENTADA project: an observational study.

    Public health·2024
    Same author

    Efficacy and safety of BNT162b2 mRNA vaccine in a cohort of 90 transfusion dependent thalassemia patients.

    Transfusion medicine (Oxford, England)·2024
    Same journal

    The role of exogenous hormones in the epidemiology of breast, ovarian and endometrial cancer.

    European journal of cancer & clinical oncology·1989
    Same journal

    Nutritional factors and cancers of the breast, endometrium and ovary.

    European journal of cancer & clinical oncology·1989
    Same journal

    Reproductive factors and cancers of the breast, ovary and endometrium.

    European journal of cancer & clinical oncology·1989
    Same journal

    Multiple primary cancers of the breast, endometrium and ovary.

    European journal of cancer & clinical oncology·1989
    Same journal

    Cancers of the breast, endometrium and ovary: geographic correlations.

    European journal of cancer & clinical oncology·1989
    Same journal

    Hormone replacement therapy in women treated for breast cancer.

    European journal of cancer & clinical oncology·1989
    See all related articles

    Clostridium difficile infection is common in leukemia patients with abdominal symptoms, often linked to antibiotic use. Early detection and treatment are crucial due to potential fatal outcomes.

    Area of Science:

    • Medical Microbiology
    • Hematology
    • Gastroenterology

    Background:

    • Leukemia patients are susceptible to infections due to compromised immune systems.
    • Abdominal symptoms in leukemia patients can indicate various complications, including infections.
    • Clostridium difficile is a known cause of infectious colitis.

    Purpose of the Study:

    • To investigate the prevalence of Clostridium difficile and its cytotoxin in leukemia patients presenting with abdominal symptoms.
    • To determine the association between Clostridium difficile infection and prior treatments in leukemia patients.
    • To highlight the clinical presentation and potential severity of Clostridium difficile in this patient population.

    Main Methods:

    • Stool samples were collected from leukemia patients experiencing diarrhea or other abdominal symptoms.

    Related Experiment Videos

  • Samples were analyzed for the presence of Clostridium difficile and its associated cytotoxin.
  • Patient treatment history, including antibiotic and cytotoxic agent use, was reviewed.

    • Main Results:

    • Clostridium difficile was detected in 19% of the studied leukemia patients.
    • The cytotoxin of C. difficile was present in most positive cases.
    • Antibiotic use was common among infected patients; one patient received only cytotoxic agents.
    • Colitis symptoms frequently presented as abdominal pain and distension, not exclusively diarrhea.

    Conclusions:

    • Clostridium difficile infection is a significant concern in leukemia patients with abdominal symptoms.
    • Routine screening for C. difficile in this high-risk group is recommended.
    • Prompt initiation of appropriate therapy is essential to manage potentially fatal outcomes.