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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones

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Construction of multifunctionalized (oxo)indoles via O-Selective interception of the zwitterionic intermediate with

Bao-Fan Wang1,2, Ziming Qiu1, Fei Lian2

  • 1School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510006, China.

Molecular Diversity
|August 5, 2025
PubMed

Keywords:
High chemical selectivityMetal carbeneMulti-component reactionsMultifunctionalized (oxo)indoles

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