Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acid-Base Balance01:25

Acid-Base Balance

1.4K
The human body maintains a narrow pH range regulated through acid-base balance. This balance is crucial as changes in the hydrogen ion concentration can disrupt cell membrane stability, alter protein structures, and change enzyme activities. The normal pH of arterial blood is 7.4, venous blood and interstitial fluid is 7.35, and intracellular fluid averages 7.0.
When the pH of arterial blood rises above 7.45, it results in a condition called alkalosis. Conversely, a drop below 7.35 leads to...
1.4K
pH Homeostasis01:31

pH Homeostasis

15.0K
Acid-base homeostasis is essential for maintaining normal physiological activities in humans. The pH of various body fluids is strictly regulated because it is critical for the optimal activity of enzymes involved in metabolic reactions. Enzymes are basically proteins, so, any significant change in pH can affect their structure and activity. In humans, pH is regulated using three primary mechanisms— chemical buffer systems, respiratory regulation, and renal regulation.
Respiratory...
15.0K
Acid–Base Equilibria: Activity-Based Definition of pH01:10

Acid–Base Equilibria: Activity-Based Definition of pH

744
For an ideal solution, the pH is defined as the negative logarithm of the hydrogen ion concentration. For a non-ideal solution, an accurate measurement of the pH must consider the negative logarithm of the hydrogen ion activity rather than concentration. In such a solution, the pH can be more accurately defined as the negative logarithm of a product of the hydrogen ion concentration and its activity coefficient.
In solutions of very low ionic strength—for example, pure water—the...
744
Bronsted-Lowry Acids and Bases02:58

Bronsted-Lowry Acids and Bases

94.4K
The acid-base reaction class has been studied for quite some time. In 1680, Robert Boyle reported traits of acid solutions that included their ability to dissolve many substances, to change the colors of certain natural dyes, and to lose these traits after coming in contact with alkali (base) solutions. In the eighteenth century, it was recognized that acids have a sour taste, react with limestone to liberate a gaseous substance (now known to be CO2), and interact with alkalis to form neutral...
94.4K
Acid–Base Titration: Overview01:26

Acid–Base Titration: Overview

11.1K
An acid-base titration is a technique used to determine the concentration of an unknown acid or base, using a titrant of known concentration–either a base for acid titration or an acid for base titration. The process involves gradually adding the titrant, leading to a predictable change in the pH of the solution. This change is plotted on a titration curve, showing how a solution's pH varies with the amount of titrant added. Such curves are instrumental in monitoring the...
11.1K
Leveling Effect and Non-Aqueous Acid-Base Solutions02:11

Leveling Effect and Non-Aqueous Acid-Base Solutions

8.4K
This lesson defines the leveling effect in acidic and basic solutions and its role in aqueous and non-aqueous solutions. It is essential to understand the competing nature of various species in a chemical system.
The Leveling Effect of a Solvent
A generic acid (HA) reacts with the generic base (B-) to yield the corresponding conjugate base (A-) and conjugate acid (HB):
8.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The missing chapter of physiology: the importance of teaching the physiology of dying.

Advances in physiology education·2026
Same author

Dissociation between gut microbiota remodeling and early gut-liver injury in CLP-induced sepsis.

Frontiers in pharmacology·2026
Same author

Sex Differences in Body Weight Regulation and Hepatic Insulin Signaling Following Bariatric Surgery and Postoperative Diet in Obese Rats.

Obesity surgery·2025
Same author

Rethinking physiology teaching: evidence and theory-informed strategies for interactive physiology education.

Advances in physiology education·2025
Same author

Biocontrol Potential of Native <i>Trichoderma</i> Strains Toward Soil-Borne Phytopathogenic and Saprotrophic Fungi.

Journal of fungi (Basel, Switzerland)·2025
Same author

Metabolic changes in Phycomyces blakesleeanus mycelia during selenite reduction and cellular localization of synthesized SeNPs.

World journal of microbiology & biotechnology·2025

Related Experiment Video

Updated: Sep 12, 2025

Author Spotlight: Experiential Tool for Teaching Active Transport Using Ex Vivo Histidine Uptake
04:40

Author Spotlight: Experiential Tool for Teaching Active Transport Using Ex Vivo Histidine Uptake

Published on: October 4, 2024

1.8K

Balancing act: enhancing student comprehension of acid-base physiology through interactive, system-based teaching.

Tamara Dakic1, Tijana Cvetic Antic2, Tanja Jevdjovic1

  • 1Department for Animal and Human Physiology, Institute for Physiology and Biochemistry "Ivan Djaja," Faculty of Biology, University of Belgrade, Belgrade, Serbia.

Advances in Physiology Education
|August 5, 2025
PubMed
Summary

This study introduces a structured teaching framework to improve undergraduate understanding of acid-base balance. The system-based approach uses active learning and concept mapping to connect physiological mechanisms with clinical applications.

Keywords:
acid-baseconcept mapsflow chartshomeostasisinteractive teaching

More Related Videos

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module
10:39

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module

Published on: June 18, 2015

13.3K
Establishment of an Extracellular Acidic pH Culture System
09:41

Establishment of an Extracellular Acidic pH Culture System

Published on: November 19, 2017

14.9K

Related Experiment Videos

Last Updated: Sep 12, 2025

Author Spotlight: Experiential Tool for Teaching Active Transport Using Ex Vivo Histidine Uptake
04:40

Author Spotlight: Experiential Tool for Teaching Active Transport Using Ex Vivo Histidine Uptake

Published on: October 4, 2024

1.8K
Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module
10:39

Using Mouse Mammary Tumor Cells to Teach Core Biology Concepts: A Simple Lab Module

Published on: June 18, 2015

13.3K
Establishment of an Extracellular Acidic pH Culture System
09:41

Establishment of an Extracellular Acidic pH Culture System

Published on: November 19, 2017

14.9K

Area of Science:

  • Physiology Education
  • Acid-Base Balance

Background:

  • Acid-base physiology is a challenging undergraduate topic due to its complexity.
  • Requires both mechanistic and integrative understanding across disciplines.

Purpose of the Study:

  • To present a structured, system-based teaching framework for acid-base balance.
  • To enhance student comprehension through active learning and conceptual integration.

Main Methods:

  • Organized into four modules: terminology, acid sources, regulatory mechanisms, and disorders.
  • Employs interactive activities: MCQs, open-ended prompts, pattern recognition, reflex analysis, concept mapping.
  • Introduces a specific sequence for concept delivery.

Main Results:

  • Facilitates linking molecular mechanisms to systemic outcomes.
  • Encourages application of knowledge to clinical and everyday scenarios.
  • Promotes deeper conceptual understanding of acid-base physiology.

Conclusions:

  • The framework enhances learning of complex acid-base concepts.
  • Active learning strategies improve integration of knowledge.
  • System-based approach aids in applying physiological principles.