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Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
Published on: June 9, 2023
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Emerging Trends in Carbon Dots as Next Generation Biomaterials
Pritesh P Khobrekar1, Ratan W Jadhav1,2, Rupesh A Kunkalkar1
1School of Chemical Sciences, Goa University, Taleigão Plateau, Panjim-Goa 403 206, India.
ACS Applied Bio Materials
|August 5, 2025
Summary
Carbon dots (CDs) are versatile nanomaterials with applications in bioimaging, biosensing, drug delivery, and phototherapy. This review summarizes their potential and challenges for clinical translation.
Area of Science:
- Biomedical Engineering
- Materials Science
- Nanotechnology
Background:
- Carbon dots (CDs) are fluorescent nanomaterials with significant potential in biological and biomedical applications.
- Their properties include biocompatibility, tunable photoluminescence, facile synthesis, functionalization ease, chemical stability, and low toxicity.
- These characteristics make CDs suitable for various biorelated fields.
Purpose of the Study:
- To provide a comprehensive summary of recent advancements in the development and application of CDs in biology.
- To highlight the versatile roles of CDs in bioimaging, biosensing, drug delivery, and phototherapy.
- To explore current challenges in translating CD technologies from research to clinical practice and outline future perspectives.
Main Methods:
- Literature review of recent advancements in carbon dot research.
- Analysis of carbon dot properties and their applications in biological fields.
- Discussion of challenges and future directions for clinical translation.
Main Results:
- Carbon dots exhibit promising potential across multiple biological and biomedical applications.
- Key applications include bioimaging, biosensing, drug delivery, and phototherapy.
- Significant challenges remain in the clinical translation of CD-based technologies.
Conclusions:
- Carbon dots are a promising class of nanomaterials for diverse biomedical applications.
- Overcoming current challenges is crucial for bridging the gap between research and clinical practice.
- Future research should focus on addressing these challenges to realize the full clinical potential of CDs.

