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[Advances in biopsy techniques for mediastinal lesions]
1Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Guangzhou Medical University, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, State Key Laboratory of Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou 510120, China.
Accurate histopathological diagnosis of mediastinal lesions guides patient management. This review covers evolving biopsy techniques, including endobronchial ultrasound and percutaneous needle biopsy, highlighting their applications and future trends.
Area of Science:
- Thoracic surgery
- Interventional pulmonology
- Diagnostic pathology
Background:
- Accurate histopathological diagnosis is crucial for managing mediastinal lesions.
- Traditional surgical biopsy remains the definitive diagnostic method.
- Minimally invasive biopsy techniques are gaining prominence.
Purpose of the Study:
- To provide a comprehensive review of current mediastinal lesion biopsy techniques.
- To summarize recent advancements and development trends in the field.
- To guide clinicians in selecting appropriate biopsy methods for different clinical scenarios.
Main Methods:
- Review of current literature on mediastinal lesion biopsy techniques.
- Discussion of endobronchial ultrasound-guided techniques (EBUS).
- Analysis of percutaneous transthoracic needle biopsy (PTNB) guided by imaging.
Main Results:
- Surgical biopsy is the gold standard but invasive.
- Endobronchial ultrasound-related techniques offer minimally invasive options.
- Image-guided percutaneous transthoracic needle biopsy is increasingly utilized.
- Technique selection depends on lesion characteristics and location.
Conclusions:
- Biopsy techniques for mediastinal lesions have advanced significantly.
- Minimally invasive approaches are becoming increasingly popular and effective.
- A comprehensive understanding of available techniques is essential for optimal patient care.
