Synthesis of 3-phenyl-3-phenylthiopropionic acids, amides, amines and studies on their pharmacological properties

The addition of mercaptobenzene to cinnamic acids yielded 3-phenyl-3-phenylthiopropionic acids which were then converted to the amides. The latter compounds were reduced to the amines with lithium aluminum hydride. Some of the obtained amides displayed significant biological activity.