User-centered design approach to visualize PROMs for molecular tumor boards

Area of Science:

• Oncology
• Health Informatics
• Data Visualization

Background:

• Integrating Patient-Reported Outcome Measures (PROMs) into Molecular Tumor Boards (MTBs) presents significant challenges.
• Current data visualization and clinical workflow integration hinder the effective use of PROMs in oncology.

Purpose of the Study:

• To identify visualization requirements for PROMs within MTBs.
• To develop and evaluate a prototype for integrating PROMs into cBioPortal for enhanced oncology care.

Main Methods:

• Qualitative research approach including persona development and co-design workshops.
• Literature-based requirements analysis and an online survey of German MTB physicians.
• Development and usability evaluation of a mid-fidelity cBioPortal prototype.

Main Results:

• Identified key visualization needs: intuitive display, clear labeling, and longitudinal tracking.
• Developed a prototype integrating PROMs into cBioPortal's timeline and a dedicated tab.
• Prototype achieved a System Usability Scale (SUS) score of 67, indicating acceptable initial usability.

Conclusions:

• PROMs offer valuable patient insights but are underutilized in MTBs.
• The developed prototype shows potential for bridging the gap in PROMs integration.
• Future work includes implementation, broader testing, and international validation for wider adoption.