Chloroquine-induced neuromyopathy. Report of a case

A patient is described in whom a neuromyopathy developed during a long chloroquine treatment for systemic lupus erythematosus (SLE). The presence of a granular deposition within the muscle fibers was observed and led to discontinuation of the drug and to a gradual recovery of muscle strength. The difficult differential diagnosis with polymyositis, steroid-induced myopathy and SLE myositis is discussed.