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Published on: March 25, 2022
Endoscopic Cholecystoduodenostomy With Lumen-Apposing Metal Stent for Bile Duct Stricture in a Child with
Maria Stella Cipriani1,2, Liliana Piro1,2, Federico Palo1
1Pediatric Surgery Department, IRCCS, Istituto Giannina Gaslini, Genoa, Italy.
Insights
Endoscopic cholecystoduodenostomy successfully treated a pediatric patient
Area of Science:
- Pediatric Surgery
- Gastroenterology
- Oncology
Background:
- A 6-year-old patient with stage M neuroblastoma (NB) underwent surgical resection after chemotherapy and stem cell transplant.
- Intraoperative injury to the common bile duct (CBD) occurred during tumor resection, necessitating repair.
Observation:
- The patient developed obstructive jaundice seven months postoperatively due to an anastomotic stricture of the CBD.
- Preoperative imaging revealed risk factors including infiltration of the porta hepatis and duodenopancreatic complex.
Findings:
- Endoscopic ultrasound-guided placement of a lumen-apposing metal stent (LAMS) created a cholecystoduodenostomy.
- This procedure successfully managed the postanastomotic stricture and relieved the jaundice.
Implications:
- Endoscopic cholecystoduodenostomy offers a novel, minimally invasive approach for managing iatrogenic CBD strictures in pediatric patients.
- Further research is needed to establish the long-term efficacy and safety of this technique.
Abstract:
We report the use of endoscopic cholecystoduodenostomy in a 6-year-old child to manage postanastomotic stricture of the common bile duct (CBD) secondary to an intraoperative injury sustained during the resection of an abdominal neuroblastoma (NB). The patient was diagnosed with stage M NB, characterized by dissemination to the bone marrow and vertebrae, and MYCN amplification. Following multiple cycles of chemotherapy and subsequent hematopoietic stem cell transplantation, the patient was scheduled for surgical resection. Preoperative imaging identified several image-defined risk factors, including infiltration of the porta hepatis and of the duodenopancreatic complex. During the dissection of the tumor, an incidental injury to the CBD occurred, which was subsequently repaired via end-to-end anastomosis. Seven months postoperatively, the patient presented with obstructive jaundice due to an anastomotic stricture, which was successfully managed through the placement of an endoscopic ultrasound-guided lumen-apposing metal stent (LAMS) between the dilated gallbladder and the duodenum. In our experience, endoscopic cholecystoduodenostomy constitutes a novel approach for addressing postoperative iatrogenic CBD strictures in pediatric patients. Further research is warranted to elucidate its benefits and risks as well as to evaluate its long-term efficacy and potential for broader application.
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