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Related Experiment Video

Updated: Sep 12, 2025

Using the Visual World Paradigm to Study Sentence Comprehension in Mandarin-Speaking Children with Autism
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Exploiting Large Language Models for Diagnosing Autism Associated Language Disorders and Identifying Distinct

Chuanbo Hu1, Wenqi Li1, Mindi Ruan2

  • 1Department of Computer Science, University at Albany, Albany, 12222, NY, USA.

Research Square
|August 6, 2025
PubMed
Summary
This summary is machine-generated.

Large Language Models (LLMs) improve autism diagnosis by analyzing language patterns, increasing sensitivity and predictive value. This technology aids in identifying key features for tailored treatment plans.

Keywords:
Autism spectrum disorder (ASD)Generative Pre-trained Transformer (GPT)Identified linguistic featuresLanguage deficitsLarge language models (LLMs)

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Area of Science:

  • Computational linguistics
  • Developmental psychology
  • Artificial intelligence in healthcare

Background:

  • Diagnosing language disorders in autism spectrum disorder (ASD) is challenging due to subjective traditional methods.
  • Existing assessment tools often lack the speed and precision required for timely diagnosis.

Purpose of the Study:

  • To explore the use of Large Language Models (LLMs) for enhancing the sensitivity and precision of autism diagnosis.
  • To identify and profile key linguistic features associated with ASD-related language disorders.

Main Methods:

  • Utilized LLMs' natural language understanding capabilities to analyze linguistic patterns in individuals with ASD.
  • Employed a zero-shot learning configuration to evaluate model performance against baseline methods.

Main Results:

  • The LLM-based approach demonstrated over a 10% increase in sensitivity and positive predictive value compared to baseline models.
  • Identified ten key linguistic features, including echolalia and pronoun reversal, crucial for ASD diagnosis.

Conclusions:

  • LLMs offer a promising, supplementary tool for improving the accuracy and efficiency of diagnosing ASD-related language patterns.
  • The identified linguistic features can inform the development of personalized treatment strategies for individuals with ASD.