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Updated: Sep 12, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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CD133 + Vesicles Mediate Resistance to RAS-ERK Inhibition Regulated by YAP Activation in Liver Cancer Cells

Shuo Zhang, Xue Feng, Evelyn Quan

    Biorxiv : the Preprint Server for Biology
    |August 6, 2025
    PubMed
    Summary

    CD133 protein forms vesicles that help cancer cells survive stress by communicating. This process is regulated by the Hippo-YAP pathway, offering new targets for liver cancer treatment.

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