Related Experiment Video
Updated: Sep 12, 2025
Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
Correlation Between Retinal Vascular Oxygen Saturation, Red Blood Cell Parameters and Hemorheology Parameters in
1Chengdu Univerisity of Taditional Chinese Medicine, Chengdu, Sichuan, People's Republic of China.
Purpose:
Investigate the correlation between retinal vascular oxygen saturation and red blood cell parameters, hemorheology parameters in healthy adults.
Methods:
The study recruited 120 healthy volunteers, and their elbow venous blood was drawn for examination of RBC parameters and hemorheology. The retinal oximeter measured the retinal vascular oxygen saturation, including retinal arteriolar oxygen saturation (SaO2), venous oxygen saturation (SvO2) and arteriovenous oxygen saturation Difference (AVD). The Pearson Correlation and Spearman's Correlation methods were used to analyze the correlation between the SaO2, SvO2, AVD and the red blood cell parameters,hemorheology parameters.
Results:
The analysis yielded a statistically significant correlation between SaO2 and BMI (r=0.184, P=0.044). SvO2 was associated with Gender (r=-0.227, P=0.013), HGB (r=-0.190, P=0.038), HCT (r=-0.236, P=0.009), RDW-CV (r=0.228, P=0.012), WBRIH (r=0.019, P=0.037), WBVL 1/s (r=-0.194, P=0.034), WBVM 50/s (r=-0.206, P=0.024), WBVH 150/s (r=-0.211, P=0.021) and WBVH 200/s (r=-0.222, P=0.015). AVD was associated with Gender (r=-0.318, P=0.000), BMI (r=0.269, P=0.003), RBC (r=0.282, P=0.002), HGB (r=0.263, P=0.004), RBCSI (r=0.187, P=0.041), WBRIH (r=0.289, P=0.001), WBRVH (r=0.247, P=0.006), WBVL 1/s (r=0.220, P=0.016), WBVL 10/s (r=0.289, P=0.001), WBVM 50/s (r=0.323, P=0.000), WBVH 150/s (r=0.320, P=0.000) and WBVH 200/s (r=0.320, P=0.000). Gender (β=-0.297, P=0.005), BMI (β=0.208, P=0.023), PV (β=-0.304, P=0.000) were independent predictors of AVD.
Conclusion:
Retinal vascular oxygen saturation is correlated with many RBC parameters and hemorheology parameters, indicating that RBC and rheological characteristics of peripheral blood may affect the transport and metabolism of retinal oxygen and are closely related to retinal microcirculation.
Translational Relevance:
The relationship between retinal blood oxygen saturation and red blood cell and hemorheology parameters confirmed the close correlation between ocular microcirculation and systemic blood circulation, which provided a prospective diagnosis and treatment strategy for microcirculatory-related eye diseases.
More Related Videos
14:28Non-Invasive Monitoring of Microvascular Oxygenation and Reactive Hyperemia using Hybrid, Near-Infrared Diffuse Optical Spectroscopy for Critical Care
Published on: May 10, 2024
04:36Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis
Published on: October 2, 2020
Related Concept Videos
01:27Oxygen Transport in the Blood
01:19Special considerations while measuring oxygen saturation
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is...
01:24Hemoglobin
When all four heme groups are bound to oxygen, the resulting molecule is called oxyhemoglobin. As a result, arterial blood...
01:17Assessment of Diffusion and Perfusion
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...
01:19Guidelines For Measuring Vital Signs
Before taking a patient's vital signs, a nurse would consider and assess the patient's comfort level and ensure appropriate equipment is available.