Refractive Predictability After Keratorefractive Lenticule Extraction Using a New Nomogram Creation Software Tool...

Area of Science:

• Ophthalmology
• Refractive Surgery
• Biomedical Engineering

Background:

• Myopia and myopic astigmatism correction surgery aims for precise refractive outcomes.
• Accurate nomograms are crucial for optimizing surgical results and patient satisfaction.
• Existing nomograms may have limitations in predicting refractive outcomes.

Purpose of the Study:

• To evaluate the efficacy of the VISULYZE nomogram software in improving refractive outcomes after lenticule extraction.
• To compare the refractive accuracy achieved with the VISULYZE nomogram versus a control group.
• To assess the impact of VISULYZE on predictability and accuracy in correcting myopia and myopic astigmatism.

Main Methods:

• An ambispective, single-site, matched case-control study involving 180 eyes.
• 90 eyes treated with VISULYZE nomogram software were compared to 90 control eyes.
• Refractive accuracy was measured at 3 months post-surgery by spherical equivalent (SEQ) and astigmatism outcomes.

Main Results:

• 98.9% of eyes in the VISULYZE group achieved SEQ within ±0.50 D, compared to 85.6% in controls (P<0.001).
• 100% of VISULYZE-treated eyes achieved astigmatism ≤0.50 D versus 93.3% in controls (P=0.006).
• VISULYZE demonstrated superior correlations for attempted vs. achieved SEQ (R²=0.9799) and astigmatism (R²=0.8996).

Conclusions:

• The VISULYZE nomogram significantly enhances refractive predictability and accuracy in lenticule extraction.
• VISULYZE software offers potential advantages for surgeons seeking improved refractive outcomes.
• This tool may represent an advancement over standard or no nomogram use in refractive surgery.