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Refractive Predictability After Keratorefractive Lenticule Extraction Using a New Nomogram Creation Software Tool
1Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu, People's Republic of China.
Purpose:
The study aimed to assess the impact of VISULYZE nomogram software on refractive outcomes after lenticule extraction for myopia and myopic astigmatism correction.
Methods:
This ambispective, single-site, matched case-control study was conducted at West China Hospital in Chengdu, China. Treatments using the VISULYZE nomogram were compared to a control group without it. The main outcome was refractive accuracy at 3 months, measured by the proportion of eyes achieving a spherical equivalent (SEQ) within ±0.50 D of the target and astigmatism ≤0.50 D.
Results:
The study involved 180 eyes, with 90 treated using VISULYZE and 90 matched controls analyzed retrospectively. In the VISULYZE group, 98.9% achieved SEQ within ±0.50 D versus 85.6% in the control group (P<0.001). Astigmatism ≤0.50 D was achieved in 100% of VISULYZE-treated eyes compared to 93.3% in controls (P=0.006). Both groups had similar safety indices. VISULYZE showed higher correlations between attempted and achieved SEQ (R²=0.9799) and astigmatism (R²=0.8996) compared to the control group (SEQ: R²=0.9590; Astig: R²=0.5992). Standard efficacy and safety measures showed no difference between groups.
Conclusion:
The VISULYZE-generated nomogram demonstrated improved predictability and accuracy in refractive outcomes. It may enhance results for surgeons compared to those using no nomogram or a standard offset nomogram.
