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Related Experiment Video

Updated: Sep 12, 2025

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
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Refractive Predictability After Keratorefractive Lenticule Extraction Using a New Nomogram Creation Software Tool

Qi Wan1, Ran Wei1, Jing Tang1

  • 1Department of Ophthalmology, West China Hospital of Sichuan University, Chengdu, People's Republic of China.

Clinical Ophthalmology (Auckland, N.Z.)
|August 6, 2025
PubMed
Summary

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Corneal Biomechanical Changes Induced by Chronic Elevated Intraocular Pressure: Implications for Glaucoma Pathogenesis and Management.

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VISULYZE-Generated Nomogram-Assisted KLEx for Myopia and Astigmatism Correction: 3-Month Follow-Up Results.

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Five years comparation of efficacy and safety after ICL-V4c implantation for high and super high myopia correction.

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Posterior lenticule laser scan influence the ultra-early postoperative visual acuity and quality of SMILE.

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Eye (London, England)·2024

The VISULYZE nomogram software significantly improved refractive accuracy for myopia and astigmatism correction surgery. It enhances surgical outcomes compared to standard methods.

Area of Science:

  • Ophthalmology
  • Refractive Surgery
  • Biomedical Engineering

Background:

  • Myopia and myopic astigmatism correction surgery aims for precise refractive outcomes.
  • Accurate nomograms are crucial for optimizing surgical results and patient satisfaction.
  • Existing nomograms may have limitations in predicting refractive outcomes.

Purpose of the Study:

  • To evaluate the efficacy of the VISULYZE nomogram software in improving refractive outcomes after lenticule extraction.
  • To compare the refractive accuracy achieved with the VISULYZE nomogram versus a control group.
  • To assess the impact of VISULYZE on predictability and accuracy in correcting myopia and myopic astigmatism.

Main Methods:

  • An ambispective, single-site, matched case-control study involving 180 eyes.
Keywords:
SMILEVISULYZElenticule extractionnomogramoutcomes

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  • 90 eyes treated with VISULYZE nomogram software were compared to 90 control eyes.
  • Refractive accuracy was measured at 3 months post-surgery by spherical equivalent (SEQ) and astigmatism outcomes.

    • Main Results:

    • 98.9% of eyes in the VISULYZE group achieved SEQ within ±0.50 D, compared to 85.6% in controls (P<0.001).
    • 100% of VISULYZE-treated eyes achieved astigmatism ≤0.50 D versus 93.3% in controls (P=0.006).
    • VISULYZE demonstrated superior correlations for attempted vs. achieved SEQ (R²=0.9799) and astigmatism (R²=0.8996).

    Conclusions:

    • The VISULYZE nomogram significantly enhances refractive predictability and accuracy in lenticule extraction.
    • VISULYZE software offers potential advantages for surgeons seeking improved refractive outcomes.
    • This tool may represent an advancement over standard or no nomogram use in refractive surgery.