Jove
Visualize
Contact Us

Related Concept Videos

Dementia01:30

Dementia

165
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
165
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

669
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
669

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Beyond Single Anthropometric Measures: Integrating Waist Circumference and Body Mass Index to Stratify Obesity-Related Health Risk.

Current obesity reports·2026
Same author

Moderators and short and long-term effects of a behavioral intervention on sedentary behavior among adults with depressive symptoms: results from a randomized clinical trial.

Journal of behavioral medicine·2026
Same author

Effect of a school-based multicomponent intervention on time-segmented physical activity and sedentary behavior among adolescents: a cluster randomized control trial.

BMC public health·2025
Same author

Sleep among Brazilian adolescents before and after the COVID-19 pandemic: repeated cross-sectional and longitudinal analyses.

BMC pediatrics·2025
Same author

Changes in Leisure-Time Physical Activity and Active Commuting to School From Before to After the COVID-19 Pandemic Among Adolescents in Brazil: Repeated Cross-Sectional and Longitudinal Analyses.

Pediatric exercise science·2025
Same author

Relationship between bullying with depressive symptoms and health-related quality of life among Brazilian high school students from Southern Brazil.

Ciencia & saude coletiva·2025
Same journal

Understanding the Struggle: Older Adults' Experiences and Coping Approaches to Low Back Pain.

Sage open aging·2026
Same journal

Diabetes-Associated Risk and Population Burden of Comorbid Conditions Among Older Adults and Elderly Persons in India.

Sage open aging·2026
Same journal

Sustaining the Long-Term Care Workforce: An Appreciative Inquiry into the Relational and Generative Factors Driving Staff Retention.

Sage open aging·2026
Same journal

Support Dynamics Among Community-Dwelling Live-Alone Persons With Dementia Who Lack Familial Care Options.

Sage open aging·2026
Same journal

Effect of Oral and Gut Microbiota, Dietary Intake, and Genetic Polymorphisms on Older Adults with Metabolic Dysfunction Associated Fatty Liver Disease.

Sage open aging·2026
Same journal

Sarcopenia Risk, Bone Turnover and Metabolic Health Indices Among Community-Dwelling Older Adults in Ghana: An Observational Study.

Sage open aging·2026
See all related articles
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Sep 12, 2025

Using a Real-Time Locating System to Measure Walking Activity Associated with Wandering Behaviors Among Institutionalized Older Adults
04:13

Using a Real-Time Locating System to Measure Walking Activity Associated with Wandering Behaviors Among Institutionalized Older Adults

Published on: February 8, 2019

6.8K

The 24-Hour Movement Behavior Composition and the Risk of Dementia.

Margarita Liubetskaya1, Marcus Vinicius Veber Lopes2, Ian Janssen1

  • 1Queen's University, Kingston, ON, Canada.

Sage Open Aging
|August 6, 2025
PubMed
Summary
This summary is machine-generated.

Optimizing your daily 24-hour movement behaviors, including sleep and physical activity, can significantly lower dementia risk. Reallocating even 15 minutes from sedentary time can reduce the likelihood of developing dementia.

Keywords:
UK Biobankcompositional data analysisdementiaphysical activitysedentary behaviorsleep

More Related Videos

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

8.3K
Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
07:26

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Published on: September 26, 2019

8.0K

Related Experiment Videos

Last Updated: Sep 12, 2025

Using a Real-Time Locating System to Measure Walking Activity Associated with Wandering Behaviors Among Institutionalized Older Adults
04:13

Using a Real-Time Locating System to Measure Walking Activity Associated with Wandering Behaviors Among Institutionalized Older Adults

Published on: February 8, 2019

6.8K
Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

8.3K
Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
07:26

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Published on: September 26, 2019

8.0K

Area of Science:

  • Gerontology
  • Neuroscience
  • Public Health

Background:

  • Dementia poses a significant global health challenge, with lifestyle factors increasingly recognized as modifiable risk factors.
  • Understanding the intricate relationship between daily time allocation across various movement behaviors and dementia incidence is crucial for preventative strategies.

Purpose of the Study:

  • To investigate the association between the composition of 24-hour movement behaviors (sleep, sedentary time, light physical activity, moderate-to-vigorous physical activity) and the risk of developing dementia.
  • To quantify the impact of reallocating time between different movement behaviors on dementia risk.

Main Methods:

  • Utilized data from 93,781 UK Biobank participants (mean age 62 years) with accelerometry-measured movement behaviors.
  • Followed participants for an average of 9.6 years to ascertain incident dementia cases.
  • Employed Cox proportional hazards models with compositional covariates to analyze the associations.

Main Results:

  • Higher relative time spent in moderate-to-vigorous physical activity and light physical activity was associated with a reduced risk of dementia.
  • Increased relative time in sedentary behavior was positively associated with a higher risk of dementia.
  • Reallocating 15 minutes daily from sedentary behavior to sleep, sedentary behavior, or physical activity decreased dementia risk by 2% to 5%.

Conclusions:

  • The composition of how time is spent across sleep, sedentary behavior, and physical activity throughout the 24-hour day is a significant determinant of dementia risk.
  • These findings highlight the importance of optimizing the entire 24-hour movement behavior spectrum for dementia prevention.