[Relation between the chemical structure and mutagenic activity of derivatives of the herbicide toluin]

Different mutagenic activities of 13 methoxy- and ethoxy-derivatives of the herbicide toluin are shown. Relationship of these activities with chemical structure is analysed. It was found out that mutagenic activity of the compound depends on its chemical structure. The higher degree of mutagenicity of analogues having-ortho-positions, as compared with the derivatives of toluin with -para- and -meta-positions was established.