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Related Experiment Video

Updated: Sep 12, 2025

Cone Beam Intraoperative Computed Tomography-based Image Guidance for Minimally Invasive Transforaminal Interbody Fusion
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Failure to Reach Early MCID in ACDF Patients.

Andrea M Roca1, Fatima N Anwar, Ishan Khosla

  • 1Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL.

Clinical Spine Surgery
|August 6, 2025
PubMed
Summary
This summary is machine-generated.

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Clinical Outcomes for Workers' Compensation versus Commercially Insured Patients Following Ambulatory Lumbar Decompression: A Cohort Matched Analysis with Two-Year Follow-Up.

World neurosurgery·2024

Predictors of early minimal clinically important difference (MCID) failure after anterior cervical discectomy and fusion (ACDF) were identified. Higher preoperative neck pain, smoking, and longer hospital stays predicted failure, while workers' compensation, better function, and less narcotic use predicted success.

Area of Science:

  • Spine Surgery
  • Patient Outcomes
  • Clinical Research

Background:

  • Limited research exists on predictors of minimal clinically important difference (MCID) failure following anterior cervical discectomy and fusion (ACDF).
  • Understanding these predictors is crucial for improving patient experiences and outcomes after ACDF.

Purpose of the Study:

  • To identify factors associated with early MCID failure after ACDF.
  • To inform strategies for mitigating negative patient outcomes post-ACDF.

Main Methods:

  • Retrospective cohort study of patients undergoing primary, elective ACDF.
  • Collected demographic, perioperative, and patient-reported outcome data (VAS-N, VAS-A, NDI, PROMIS-PF, SF-12 PCS/MCS, PHQ-9).
  • Utilized two-step multivariable logistic regression to determine predictors of MCID failure.
Keywords:
anterior cervical discectomy and fusioncervical spineminimal clinically important differenceoutcomes

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Last Updated: Sep 12, 2025

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Main Results:

  • Preoperative neck pain (VAS-N), foraminal stenosis diagnosis, smoking status, and longer length of stay were positive predictors of failure.
  • Workers' compensation status, preoperative physical function (PROMIS-PF), mental health scores (SF-12 MCS), physical component scores (SF-12 PCS), and postoperative narcotic consumption were negative predictors of failure.

Conclusions:

  • Early MCID failure after ACDF is associated with specific patient and perioperative factors.
  • Identifying these predictors allows for proactive management to enhance patient satisfaction and surgical success.
  • Factors such as preoperative pain, smoking, and length of stay require attention, while positive indicators include workers' compensation, better baseline function, and lower narcotic use.