Related Experiment Video
Updated: Sep 12, 2025

Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
Published on: May 17, 2019
Readability analysis of breast cancer resources shared on X-implications for patient education and the potential of
Melanie J Wang1, Aref Rastegar1, Theodore A Kung2
1Department of Surgery, Section of Plastic Surgery, University of Michigan, Ann Arbor, MI, USA.
Purpose:
Breast cancer remains a global public health burden. This study aimed to evaluate the readability of breast cancer articles shared on X (formerly Twitter) during Breast Cancer Awareness Month (October 2024), and it explores the possibility of using artificial intelligence (AI) to improve readability.
Methods:
We identified the top articles (n = 377) from posts containing #breastcancer on X during October 2024. Each article was analyzed using 9 established readability tests: Automated Readability Index (ARI), Coleman-Liau, Flesch-Kincaid, Flesch Reading Ease, FORCAST Readability Formula, Fry Graph, Gunning Fog Index, Raygor Readability Estimate, and Simple Measure of Gobbledygook (SMOG) Readability Formula. The study categorized sharing entities into five groups: academic medical centers, healthcare providers, government institutions, scientific journals, and all others. This comprehensive approach aimed to evaluate the readability of breast cancer articles across various sources during a critical awareness period of peak public engagement. A pilot study was simultaneously conducted using AI to improve readability. Statistical analysis was performed using SPSS.
Results:
A total of 377 articles shared by the following entities were analyzed: academic medical centers (35, 9.3%), healthcare providers (57, 15.2%), government institutions (21, 5.6%), scientific journals (63, 16.8%), and all others (199, 53.1%). Government institutions shared articles with the lowest average readability grade level (12.71 ± 0.79). Scientific journals (16.57 ± 0.09), healthcare providers (15.49 ± 0.32), all others (14.89 ± 0.17), and academic medical centers (13.56 ± 0.39) had higher average readability grade levels. Article types were also split into different categories: patient education (222, 58.9%), open-access journal (119, 31.5%), and full journal (37, 9.6%). Patient education articles (15.19 ± 0.17) had the lowest average readability grade level. Open-access and full journals had an average readability grade level of 16.65 ± 0.06 and 16.53 ± 0.10, respectively. The mean values for Flesch Reading Ease Score are patient education 38.14 ± 1.2, open-access journals 16.14 ± 0.89, full journals 17.69 ± 2.14. Of note, lower readability grade levels indicate easier-to-read text, while higher Flesch Reading Ease scores indicate more ease of reading. In a demonstration using AI to improve readability grade level of 5 sample articles, AI successfully lowered the average readability grade level from 12.58 ± 0.83 to 6.56 ± 0.28 (p < 0.001).
Conclusions:
Our findings highlight a critical gap between the recommended and actual readability levels of breast cancer information shared on a popular social media platform. While some institutions are producing more accessible content, there is a pressing need for standardization and improvement across all sources. To address this issue, sources may consider leveraging AI technology as a potential tool for creating patient resources with appropriate readability levels.
Related Concept Videos
Cancer Survival Analysis
Issues And Trends In Healthcare Delivery System
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cancer-Critical Genes II: Tumor Suppressor Genes
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...
Adaptive Mechanisms in Cancer Cells
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Combination Therapies and Personalized Medicine
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

