Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neural Regulation of Blood Pressure01:18

Neural Regulation of Blood Pressure

3.4K
The neural regulation of blood pressure involves intricate interactions between the autonomic nervous system (ANS) and cardiovascular system, ensuring adequate perfusion of tissues. This regulation primarily occurs through baroreceptor and chemoreceptor reflexes, involving both short-term and long-term mechanisms.
Baroreceptor Reflex
Baroreceptors, located in the carotid sinuses and aortic arch, detect changes in blood pressure. When blood pressure rises, these stretch-sensitive receptors...
3.4K
Equipments Used To Measure Blood Pressure01:30

Equipments Used To Measure Blood Pressure

2.4K
Direct Method
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
2.4K
Sites for measruring blood pressure01:21

Sites for measruring blood pressure

2.4K
Blood pressure measurement is a fundamental clinical procedure, providing crucial data for assessing cardiovascular health. Among the various sites for this measurement, the brachial and popliteal arteries are predominantly utilized due to their accessibility and the reliability of their readings. This lesson delves into the anatomical significance, methodology, and considerations of measuring blood pressure at these locations.
The Brachial Artery: Primary Site for Blood Pressure Measurement
2.4K
Pulse rhythm01:30

Pulse rhythm

927
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
927
Errors occurring during blood pressure monitoring01:25

Errors occurring during blood pressure monitoring

971
Blood pressure monitoring is a crucial clinical procedure in diagnosing and managing various cardiovascular conditions. Despite its significance, the accuracy of blood pressure measurements can be compromised by multiple factors, potentially leading to either falsely high or low readings. These inaccuracies are critical as they can significantly impact patient care. So, it is vital to understand these challenges deeply and adopt strategic approaches to minimize errors.
Several factors...
971
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

1.5K
Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Thrombin-conjugated cationic nanogels loaded with CpG enhance tumor vessel infarction by interpenetrating double gel network and immune activation.

Colloids and surfaces. B, Biointerfaces·2026
Same author

Potential Role of METTL14 in Modulating Prostate Cancer Proliferation and Glycolysis Through m6A Modification of LINC01138.

Applied biochemistry and biotechnology·2026
Same author

Aspirin prevents postoperative peritoneal adhesions by inhibiting the TGF‑β1/Smad signaling pathway in rats.

Molecular medicine reports·2026
Same author

Cold-Driven Thermoelectric Patch for Postoperative Tumor Control.

ACS nano·2026
Same author

A coupled heat-cold island network framework for urban heat island mitigation: a case study of Central Fuzhou.

Scientific reports·2026
Same author

Bleb Revision Techniques for Hypotony Maculopathy: A Review.

International ophthalmology clinics·2026

Related Experiment Video

Updated: Sep 12, 2025

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
04:24

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

Published on: April 19, 2019

11.7K

A closed-loop bioelectronic patch for intelligent blood pressure management.

Yuyan Zou1, Zeguo Chen2, Bowen Jin1

  • 1Hunan Provincial Key Laboratory of Micro and Nano Materials Interface Science, College of Chemistry and Chemical Engineering, Central South University, Changsha, Hunan 410083, China.

Science Advances
|August 6, 2025
PubMed
Summary
This summary is machine-generated.

This study presents an intelligent blood pressure management system (BPMS) for real-time monitoring and intervention. The system uses microneedles to deliver nitric oxide (NO), enabling on-demand vasodilation for cardiovascular disease management.

More Related Videos

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring
06:29

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring

Published on: May 2, 2025

292
Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.5K

Related Experiment Videos

Last Updated: Sep 12, 2025

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program
04:24

A Novel Digital Platform for a Monitored Home-based Cardiac Rehabilitation Program

Published on: April 19, 2019

11.7K
Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring
06:29

Wireless Telemetry Device Implantation in a Fontan Ovine Model for Continuous and Long-Term Hemodynamic Monitoring

Published on: May 2, 2025

292
Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
08:19

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

14.5K

Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Cardiovascular Medicine

Background:

  • Cardiovascular diseases are a major cause of death, often due to delayed drug interventions.
  • Current treatments lack real-time monitoring and adaptive therapeutic responses.
  • There is a need for innovative systems for continuous blood pressure management.

Purpose of the Study:

  • To develop an intelligent blood pressure management system (BPMS) for real-time monitoring and adaptive intervention.
  • To create a closed-loop framework integrating sensors, control circuits, and microneedle electrodes for precise NO delivery.
  • To investigate the efficacy of a novel microneedle architecture for on-demand vasodilation.

Main Methods:

  • Designed a hierarchical microneedle architecture with gold nanoparticle (Au NP) electrocatalysts and copper-nitrogen-doped carbon nanoribbon (Cu-NC NB) nanozymes.
  • Utilized an electroosmotic flow (EOF) mechanism for enhanced nitric oxide (NO) delivery up to 4 mm.
  • Integrated sensors and control circuits for a closed-loop BPMS framework.
  • Conducted in vivo studies in rabbits and pigs to evaluate hemodynamic control.

Main Results:

  • The BPMS demonstrated dynamic regulation of NO release in response to blood pressure fluctuations.
  • Achieved real-time hemodynamic control through on-demand vasodilation.
  • The porous microneedle (PMN) array facilitated effective vascular penetration and NO diffusion.
  • Successfully validated the system's efficacy in animal models.

Conclusions:

  • Pioneered a closed-loop strategy for continuous blood pressure monitoring and on-demand vasodilation.
  • The developed BPMS offers a transformative approach to intelligent cardiovascular disease management.
  • The novel microneedle-based NO delivery system shows significant potential for therapeutic applications.