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Testing a 5-fraction Simultaneous Integrated Boost in Radiotherapy for Breast Cancer: The UK FAST-Forward Boost Trial

A M Kirby1, F H Cafferty2, K Poole2

  • 1Royal Marsden NHS Foundation Trust & Institute of Cancer Research, Downs Road, Sutton, Surrey SM2 5PT, UK.

Clinical Oncology (Royal College of Radiologists (Great Britain))
|August 6, 2025
PubMed
Summary

No abstract available in PubMed .

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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