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  11. Somatic Disease Burden In Parents Of Children With Cancer - A Nationwide Cohort Study In Sweden

Somatic disease burden in parents of children with cancer - a nationwide cohort study in Sweden

Yishan Liu1, Filip Jansåker2, Jan Sundquist2

  • 1Center for Primary Health Care Research, Department of Clinical Sciences Malmö, Lund University, Sweden.

Preventive Medicine
|August 6, 2025

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View abstract on PubMed

Summary
This summary is machine-generated.

Parents of children with cancer face increased rates of recurrent somatic health conditions, highlighting the long-term physical health burden. This underscores the need for better parental support systems.

Area of Science:

  • Oncology
  • Public Health
  • Epidemiology

Background:

  • Childhood cancer diagnosis significantly impacts families, particularly parental mental health.
  • The long-term somatic health consequences for parents of children with cancer are not well understood.
  • Persistent somatic diseases in parents can lead to frequent healthcare utilization and reduced quality of life.

Purpose of the Study:

  • To investigate the long-term cumulative burden of somatic health conditions in parents of children diagnosed with cancer.
  • To compare the rates of recurrent somatic health events between parents of children with cancer and control groups.

Main Methods:

  • Utilized Swedish national registers to identify parents of children diagnosed with cancer (before age 14) between 1987-2016.
  • Matched cases with up to five controls (parents of children without cancer).
Keywords:
Childhood cancerHealth promotionNationwide cohortParental somatic health

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  • Analyzed parental somatic health conditions (14 major disease groups) using the National Patient Register and primary health care data until 2018, employing a marginal means/rates model for recurrent events.

    • Main Results:

    • Identified 6,859 fathers and 7,098 mothers of children with cancer, followed for up to 32 years.
    • Parents of children with cancer showed higher rates of recurrent somatic health conditions (84.14 vs. 80.63 per 1000 person-months).
    • Increased risks were observed across neoplasms, blood/immune diseases, circulatory diseases, and genital organ diseases, with variations across subgroups.

    Conclusions:

    • Having a child diagnosed with cancer is associated with significant long-term somatic health consequences for parents.
    • Findings emphasize the need for targeted supportive interventions to alleviate parental stress and enhance somatic well-being.
    • Further research into specific risk factors and effective support strategies is warranted.
    Recurrent event model