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Updated: Sep 12, 2025
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Published on: March 6, 2018
Does Metabolic Syndrome Influence Surgical Success? Outcomes of Transurethral Resection of Prostate and Open
Mahmut Uğurlu1, Cihat Aytekin1, Muratcan Toptaş1
1Urology Department, Gazi University Medical Faculty, Ankara, Turkey.
Objective:
This study aimed to compare the perioperative outcomes of open prostatectomy (OP) and transurethral resection of the prostate (TURP) in patients with large-volume benign prostatic hyperplasia (BPH) and to evaluate the impact of metabolic syndrome (MetS) on surgical outcomes.
Materials And Methods:
In this retrospective study, 239 patients with a prostate volume greater than 80 cc who underwent TURP (n = 122) or OP (n = 117) between 2018 and 2024 were included. MetS was diagnosed according to NCEP-ATP III 2005 criteria. Postoperative IPSS, Qmax, PVR, hemoglobin levels, and complication rates were compared between groups and by MetS status.
Results:
Both groups demonstrated significant improvements in IPSS and Qmax postoperatively (p < 0.001). MetS did not significantly impact postoperative IPSS, Qmax, or PVR in either group (p > 0.05). MetS components such as HDL, triglycerides, and waist circumference showed no meaningful correlation with surgical outcomes.
Discussion:
In patients with large prostate volumes, both surgical techniques yielded significant symptomatic improvement; while metabolic syndrome did not significantly influence postoperative IPSS, Qmax, or PVR outcomes.
