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Updated: Sep 12, 2025

Protocol to Create Chronic Wounds in Diabetic Mice
Published on: September 25, 2019
RETRACTION: The Role of Orthobiologics in Chronic Wound Healing
Retraction:
R. Barnabé Domingues, M. von Rautenfeld, C. M. Kavalco, C. Caliari, C. Dellagiustina, L, Furtado da Fonseca, F. Ramos Costa, A. da Cruz Silva Reis, G. Silva Santos, G. Azzini, A. Pinto Lemos de Faria, N. Santos, L. Pires, S. Cares Huber, A. Mahmood, I. Dallo, P. Everts, and J. Fábio Lana, "The Role of Orthobiologics in Chronic Wound Healing," International Wound Journal 21, no. 4 (2024): e14854, https://doi.org/10.1111/iwj.14854. The above article, published online on 15 April 2024 in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor in Chief, Professor Keith Harding; and John Wiley & Sons, Ltd. An investigation by the publisher found that the article contained significant textual overlap between this article and other articles by different authors [1-3]. Additional textual overlap was also detected in multiple other articles [4-7]. While each of the reference articles noted in this retraction was included as a reference in the published article, the overlap extended to entire passages that were copied verbatim and not included in quotation marks. The authors responded to an inquiry by the publisher and stated that some technical language and common terms for physiological mechanisms and biochemical actions of orthobiologics may have contributed to the findings of significant textual overlap. A review of the textual overlap by the publisher found that it constituted significant plagiarism which could not be amended through correction. As such, all parties have agreed that the article must be retracted. The authors did not agree with the retraction. The authors disagree with the retraction. REFERENCES: [1] R. G. Frykberg and J. Banks, "Challenges in the Treatment of Chronic Wounds," Advances in Wound Care 4, no. 9 (2015): 560-582, https://doi.org/10.1089/wound.2015.0635. [2] Jo H. Brito S. Kwak B. M. Park S. Lee M.-G. Bin B.-H. Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation International Journal of Molecular Sciences 22 no. 5 2021 2410 https://doi.org/10.3390/ijms22052410 [3] Everts P. Onishi K. Jayaram P. Lana J. F. Mautner K. Platelet-Rich Plasma: New Performance Understandings and Therapeutic Considerations in 2020 International Journal of Molecular Sciences 21 20 2020 7794 https://doi.org/10.3390/ijms21207794 [4] Everts P. Sadeghi P. Smith D. R. Basic Science of Autologous Orthobiologics: Part 1. Platelet-Rich Plasma Physical Medicine and Rehabilitation Clinics of North America 34 1 2023 1 23 https://doi.org/10.1016/j.pmr.2022.08.003 [5] V. Popescu, V. Cauni, M. S. Petrutescu, M. M. Rustin, R. Bocai, C. R. Turculet, H. Doran, T. Patrascu, A. M. Lazar, D. Cretoiu, V. N. Varlas, and B. Mastalier, "Chronic Wound Management: From Gauze to Homologous Cellular Matrix," Biomedicines 11, no. 9 (2023): 2457, https://doi.org/10.3390/biomedicines11092457. [6] J. F. S. D. Lana, A. V. S. D. Lana, L. F. da Fonseca, M. A. Coelho, G. G. Marques1, T. Mosaner, L. L. Ribeiro, G. O. M. Azzini, G. S. Santos, E. Fonseca, and M. A. P. de Andrade, "Stromal Vascular Fraction for Knee Osteoarthritis - An Update," Journal of Stemcells & Regenerative Medicine 18, no. 1 (2022): 11-20, https://doi.org/10.46582/jsrm.1801003. [7] M. J. Martinez-Zapata A. J Martí-Carvajal I. Solà J. A. Expósito I. Bolíbar L. Rodríguez J. Garcia C. Zaror Autologous Platelet-Rich Plasma for Treating Chronic Wounds Cochrane Database of Systematic Reviews 2016 2016 CD006899 https://doi.org/10.1002/14651858.CD006899.pub3 5.
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