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Updated: Sep 12, 2025

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
Published on: October 25, 2024
[Pulmonary Embolism: Current Challenges and Future Directions]
I A Merkulova1, N S Germanov1, Z B Bashankaeva1
1Chazov National Medical Research Center of Cardiology.
Abstract:
Pulmonary embolism (PE) is a complex emergency condition, the diagnosis and treatment of which still have many unresolved issues and "gray areas". Current clinical guidelines for the management of patients with PE are partly outdated and do not take into account a number of modern data. In this review, the authors identified unresolved issues and provided the latest data on the assessment of pre-test probability, risk stratification, diagnosis and treatment of acute PE, particularly in patients with intermediate-high and high risk of death. The issues of reperfusion catheter techniques and intensive care are addressed individually. The requirement for specialized PE centers of expert level and their prospects are discussed.
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