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Updated: Sep 12, 2025

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Left Ventricular Assist Device in the Management of Heart Failure: A Single-Center Experience

Sam Karem1, Rajasekhar S R Malyala2, Sibu Saha3

  • 1MS3 at University of Kentucky College of Medicine, Lexington, Kentucky.

The International Journal of Angiology : Official Publication of the International College of Angiology, Inc
|August 7, 2025
PubMed

Insights

Left ventricular assist device (LVAD) therapy helps manage advanced heart failure. This study reviewed LVAD outcomes at the University of Kentucky, finding improvements in quality of life for many patients despite noted complications.

Area of Science:

  • Cardiology
  • Medical Devices
  • Heart Failure Management

Background:

  • Heart failure is a significant healthcare challenge in the US.
  • Left ventricular assist devices (LVADs) offer a solution for medically intractable heart failure cases.

Purpose of the Study:

  • To evaluate the outcomes of left ventricular assist device (LVAD) therapy.
  • To assess patient quality of life post-LVAD implantation at the University of Kentucky.

Main Methods:

  • Retrospective review of patient records for LVAD implantation.
  • Data collected from January 1, 2017, to December 31, 2021.
  • Analysis included patient demographics, length of stay, quality of life (NYHA classification), survival rates, and postoperative complications.

Main Results:

  • 127 eligible patients (age 18-83) received LVADs.
  • Significant improvements in New York Heart Association (NYHA) functional classification were observed.
  • Reported postoperative complications included stroke (26%), gastrointestinal bleeding (24.4%), renal failure (26%), respiratory failure (44.8%), driveline infection (37%), and right ventricular dysfunction (14.2%).

Conclusions:

  • Left ventricular assist device (LVAD) implantation is a viable strategy for managing advanced heart failure.
  • LVAD therapy can improve patient quality of life.
  • Careful monitoring for and management of postoperative complications are crucial for successful LVAD outcomes.
Abstract

Keywords:
LVADheart failureleft ventricular assist device

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