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Can carbonated water support weight loss?
1Dialysis Center, Tesseikai Neurosurgery Hospital, Shijonawate, Japan.
BMJ Nutrition, Prevention & Health
|August 7, 2025
Summary
Carbonated water may enhance glucose metabolism in red blood cells due to absorbed carbon dioxide (CO2). However, the effect is minimal, and further research is needed on its impact on weight loss and blood glucose measurements.
Area of Science:
- Physiology
- Biochemistry
Background:
- Carbonated water consumption is linked to satiety, gastric motility, and reduced serum glucose.
- The precise physiological mechanisms behind these effects remain largely unelucidated.
Purpose of the Study:
- To explore the physiological effects of carbonated water.
- To investigate the role of carbon dioxide (CO2) absorption in glucose metabolism.
Main Methods:
- Literature review referencing a 2004 study on hemodialysis-induced hypoglycemia.
- Analysis of CO2 conversion to bicarbonate in erythrocytes and its impact on intracellular pH and glucose utilization.
Main Results:
- Carbon dioxide (CO2) absorption increases erythrocyte intracellular pH, stimulating anaerobic glycolysis and enhancing glucose utilization.
- A comparison with hemodialysis demonstrates similar CO2-driven glucose metabolism, evidenced by decreased blood glucose levels post-dialysis.
Conclusions:
- Carbonated water's CO2 may promote weight loss via enhanced erythrocyte glucose uptake, though the effect is likely small.
- Potential impacts on blood glucose measurements warrant further investigation, alongside long-term effects and side effects.
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