Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

MALDI-TOF Mass Spectrometry01:19

MALDI-TOF Mass Spectrometry

5.2K
Mass spectrometry is a powerful characterization technique that can identify and separate a wide variety of compounds ranging from chemical to biological entities, based on their mass-to-charge ratio (m/z). The instruments that allow this detection, known as mass spectrometers, have three components: an ion source, a mass analyzer, and a detector. These spectrometers differ based on the nature of their ion source and analyzers.
Matrix-assisted laser desorption ionization (MALDI) is a commonly...
5.2K
Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

601
The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and...
601
Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

532
A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...
532

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Plasmonic trimer nanoarrays with probe-trapping sites for SERS detection of urinary copper in Wilson's disease.

The Analyst·2026
Same author

Charge-Transfer Enhanced SERS on MoO<sub>2</sub> Nanoparticles with Ultrahigh Sensitivity and Exceptional Environmental Robustness.

ACS applied materials & interfaces·2026
Same author

Systematic investigation of the LSPR characteristics in plasmonic nanoarrays.

Microsystems & nanoengineering·2026
Same author

Geometry-Engineered Pd-Au Plasmonic Nanoarrays: Unveiling Design Principles for High-Performance Hydrogen Sensing.

The journal of physical chemistry letters·2026
Same author

Plasmonic Nanoarrays as SERS Substrates: Advances, Challenges, and Perspectives.

Accounts of chemical research·2026
Same author

Morphology-adaptive Au-Ag nanowire elastronics for integrated FlexoSERS and bioelectrical sensing.

Science advances·2026

Related Experiment Video

Updated: Sep 12, 2025

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

1.6K

Challenges and Prospects of Personalized Healthcare Based on Surface-Enhanced Raman Spectroscopy.

Guoqun Li1, Xingce Fan1, Xiao Tang1

  • 1Key Laboratory of Quantum Materials and Devices of Ministry of Education, School of Physics, Southeast University, Nanjing 211189, China.

Research (Washington, D.C.)
|August 7, 2025
PubMed
Summary
This summary is machine-generated.

Flexible surface-enhanced Raman spectroscopy (SERS) chips offer rapid, molecular-level insights for personalized healthcare monitoring. These advanced biosensors, combined with AI, promise early disease detection and improved health management.

More Related Videos

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.6K
Rejection of Fluorescence Background in Resonance and Spontaneous Raman Microspectroscopy
15:04

Rejection of Fluorescence Background in Resonance and Spontaneous Raman Microspectroscopy

Published on: May 18, 2011

13.2K

Related Experiment Videos

Last Updated: Sep 12, 2025

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging
06:19

Author Spotlight: Advancing SERS Technology: Au@Carbon Dot Nanoprobes for Label-Free Analysis and Imaging

Published on: June 9, 2023

1.6K
Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates
11:44

Surface Enhanced Raman Spectroscopy Detection of Biomolecules Using EBL Fabricated Nanostructured Substrates

Published on: March 20, 2015

20.6K
Rejection of Fluorescence Background in Resonance and Spontaneous Raman Microspectroscopy
15:04

Rejection of Fluorescence Background in Resonance and Spontaneous Raman Microspectroscopy

Published on: May 18, 2011

13.2K

Area of Science:

  • Nanotechnology and Advanced Materials Science
  • Biomedical Engineering
  • Analytical Chemistry

Background:

  • Personalized healthcare monitoring leverages molecular insights for risk prevention and health enhancement.
  • Nanotechnology, smart devices, and AI are revolutionizing personalized healthcare, particularly point-of-care testing (POCT).
  • Surface-enhanced Raman spectroscopy (SERS) offers in situ, rapid, specific, and efficient detection capabilities.

Purpose of the Study:

  • To review recent advancements in flexible SERS chips for personalized healthcare monitoring.
  • To demonstrate the effectiveness of flexible SERS chips in target sampling and detection.
  • To provide a comprehensive overview of applications, challenges, and future directions for flexible SERS in healthcare.

Main Methods:

  • Review of recent literature on flexible SERS chip technology.
  • Analysis of SERS capabilities for in situ, rapid, specific, and efficient molecular detection.
  • Exploration of AI integration for data processing and analysis in SERS-based monitoring.

Main Results:

  • Flexible SERS chips show significant promise for personalized healthcare monitoring.
  • Demonstrated effectiveness in target sampling and detection for various health indicators.
  • AI enhances data analysis, improving the utility of SERS in healthcare applications.

Conclusions:

  • Flexible SERS chips are a key technology for advancing personalized healthcare monitoring.
  • Integration with AI and miniaturized devices will broaden their application scope.
  • SERS technology heralds a new era of proactive and personalized health management.