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Published on: November 8, 2011
Giant cutaneous ulcer in Epstein-Barr virus positive T-cell/NK-cell lymphoproliferative disorder: A case report
Ya-Ping Guo1, Zhi-Xin Wang1, Shu-Li Guo2
1Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.
Background:
Epstein-Barr virus (EBV)-positive T-cell/natural killer (NK)-cell lymphoproliferative disorder is a rare but challenging condition that requires multidisciplinary teamwork, including co-management by infection medicine, radiotherapy, rehabilitation, and psychology experts, as well as wound specialist nurses.
Case Summary:
The patient was a 33-year-old female who presented with an erythema-like lesion on the left upper extremity that became desquamated and then blistered and eventually became a giant ulcer with exposed nerves and muscles. The left wrist had a fixed posture, and pathology tests showed cutaneous EBV-positive NK/T-cell proliferative disease. We employed a multidisciplinary collaborative treatment approach, and after 13 wound changes over 45 days, combined with radiation therapy, dietary supplementation, and psychosocial therapy, the left upper extremity wound healed.
Conclusion:
Giant ulcers caused by cutaneous EBV-positive NK/T-cell proliferative disease can be treated using a multidisciplinary collaborative approach.
