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Visualization of Streptococcus pneumoniae within Cardiac Microlesions and Subsequent Cardiac Remodeling
08:25

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Published on: April 7, 2015

Group C streptococcal endocarditis: case report and review of the literature

D S Stein, A P Panwalker

    Infection
    |November 1, 1985
    PubMed

    Insights

    Group C streptococcal endocarditis is a rare but serious infection. Early treatment with penicillin and aminoglycosides, and potentially valve replacement, may improve outcomes for this severe heart valve condition.

    Area of Science:

    • Infectious Diseases
    • Cardiology
    • Microbiology

    Background:

    • Group C streptococci (GCS) are uncommon causes of human infections.
    • Endocarditis, an infection of the heart valves, is a severe condition.
    • This study focuses on GCS endocarditis, a rare clinical presentation.

    Observation:

    • A case of endocarditis caused by group C streptococci is presented.
    • A literature review identified 16 additional cases of GCS endocarditis.
    • The organism demonstrated a propensity for infecting and damaging healthy heart valves.

    Findings:

    • GCS endocarditis is associated with a high risk of major emboli to vital organs.
    • Mortality rates for GCS endocarditis are notably high.
    • Penicillin combined with an aminoglycoside showed lower morbidity than penicillin alone.

    Implications:

    • Prompt diagnosis and treatment are crucial for managing GCS endocarditis.
    • Synergistic antibiotic therapy (penicillin and aminoglycoside) may be more effective.
    • Early surgical intervention, including valve replacement, could reduce mortality in severe cases.

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