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Published on: March 14, 2025
Mindfulness for obsessive-compulsive disorder: a systematic review and meta-analysis
Eduardo Aliende Perin1, Nelson Carvas Junior1, Vinicius Tassoni Civile1
1Programa de Saúde Baseada em Evidencia, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brazil.
Mindfulness-based interventions (MBIs) show no significant difference compared to other treatments for obsessive-compulsive disorder (OCD). While MBIs slightly improved mindfulness skills, they did not substantially reduce OCD symptoms, anxiety, or depression.
Area of Science:
- Psychiatry
- Clinical Psychology
- Behavioral Science
Background:
- Obsessive-compulsive disorder (OCD) is a debilitating mental health condition.
- Mindfulness-based interventions (MBIs) have been explored as a potential treatment for OCD.
- The current evidence on the efficacy of MBIs for OCD is limited and requires further investigation.
Purpose of the Study:
- To systematically review and meta-analyze the effectiveness of mindfulness-based interventions (MBIs) in treating adults with obsessive-compulsive disorder (OCD).
- To compare MBIs against active control interventions, including established OCD treatments.
Main Methods:
- Systematic review and meta-analysis of randomized controlled trials (RCTs).
- Inclusion of six RCTs with 499 adult participants.
- Primary outcomes assessed included obsessive-compulsive symptoms, dropout rates, anxiety, depressive symptoms, mindfulness skills, and quality of life.
Main Results:
- Mindfulness-based interventions (MBIs) did not demonstrate significant superiority over other active treatments in reducing obsessive-compulsive symptoms.
- No significant differences were found in dropout rates, anxiety, or depressive symptoms between MBIs and control groups.
- A minor, non-clinically relevant improvement in mindfulness skills was observed, while quality of life outcomes were inconsistent.
Conclusions:
- Mindfulness-based interventions (MBIs) are not significantly more effective than established treatments like exposure with response prevention (ERP), psychoeducation, and cognitive restructuring for OCD.
- Current evidence suggests MBIs do not offer a distinct advantage for core OCD symptom reduction.
- Further research may be needed to explore specific patient subgroups or adjunctive roles for MBIs in OCD treatment.
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