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Mediastinal foregut duplication cyst presenting as acute respiratory distress in a three-month-old infant: A case
Abdullah Bin Usman1, Arooba Usman2, Usman Javaid3
1Medical University Sofia, Sofia, Bulgaria.
Insights
Foregut duplication cysts in neonates can mimic common conditions, leading to diagnostic delays. Early multimodal imaging and complete surgical excision are crucial for successful outcomes in infants with these rare mediastinal malformations.
Area of Science:
- Pediatric Surgery
- Diagnostic Imaging
- Congenital Malformations
Background:
- Foregut duplication cysts are rare mediastinal malformations.
- They can cause severe respiratory compromise in infants.
- Initial imaging may lead to misdiagnosis as other conditions.
Observation:
- A 3-month-old infant presented with progressive respiratory distress and cyanosis.
- Chest radiography suggested a hiatal hernia; ultrasound revealed a multiloculated cyst.
- Contrast-enhanced CT precisely delineated the cyst's extent.
Findings:
- A large paracardial cyst and a smaller posterior cyst were identified.
- En-bloc surgical removal was performed via a thoraco-abdominal approach.
- Histology confirmed a gastric-type foregut duplication cyst.
Implications:
- This case highlights diagnostic challenges and the importance of multimodal imaging.
- Complete surgical excision is vital to prevent complications like infection or malignant transformation.
- Prompt diagnosis and surgical intervention ensure excellent long-term outcomes for neonates.
Introduction:
Foregut duplication cysts are rare mediastinal malformations that can cause life-threatening respiratory compromise in early infancy and are often misdiagnosed on initial imaging.
Presentation Of Case:
A three-month-old boy, born at 37 weeks, developed progressive respiratory distress and cyanosis unresponsive to pneumonia therapy. Chest radiography suggested a hiatal hernia, whereas thoracic ultrasound showed a multiloculated cyst. Contrast-enhanced CT delineated a thick-walled paracardial cyst crossing the diaphragm and a smaller posterior chest-wall cyst. On hospital day 8 a right thoraco-abdominal approach allowed en-bloc removal of the 6 × 4 cm lesion with mucosectomy of the adherent esophageal segment and excision of the posterior cyst. Histology confirmed gastric-type foregut duplication. The infant was extubated on postoperative day 1, reached full feeds by day 7, and was discharged asymptomatic on day 18.
Discussion:
This case illustrates the diagnostic pitfalls of mediastinal foregut duplication cysts masquerading as more common entities such as hiatal hernia. Multimodal imaging-particularly ultrasound and CT-was pivotal in defining lesion extent and guiding timely surgery. Complete thoraco-abdominal excision achieved rapid recovery and mitigated risks of infection, hemorrhage, or malignant transformation reported with incomplete resection.
Conclusion:
Neonates with unexplained respiratory distress and mediastinal masses should prompt consideration of foregut duplication cysts. Early cross-sectional imaging and definitive surgical excision are essential for preventing complications and ensuring excellent long-term outcomes.
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