Related Experiment Video
Updated: Sep 12, 2025

Treatment with Vancomycin Loaded Calcium Sulphate and Autogenous Bone in an Improved Rabbit Model of Bone Infection
Published on: March 14, 2019
Paediatric type I open tibia fractures: are antibiotics alone sufficient?
Rory F L Hammond1, Nikhil Manoj2, Anna Bridgens3
1The Royal London Hospital, London, UK.
Insights
For pediatric Gustilo-Anderson type I open tibia fractures, nonoperative management with antibiotics showed similar infection rates to operative debridement. Further high-quality evidence is needed to guide treatment decisions for these pediatric fractures.
Area of Science:
- Orthopedic Surgery
- Pediatric Trauma
- Infectious Disease
Background:
- Conventional management of open fractures includes emergent debridement.
- Evidence suggests questioning this approach for pediatric Gustilo-Anderson type I open fractures.
Purpose of the Study:
- To systematically review infection rates comparing nonoperative management (antibiotics) versus operative debridement.
- Focus on pediatric type I open lower limb tibial fractures without need for surgical fixation.
Main Methods:
- Systematic review adhering to PRISMA guidelines.
- Included patients under 18 with type I open tibia fractures.
- Excluded polytrauma and those needing operative stabilization.
- Assessed bias using ROBINS-I tool.
Main Results:
- Ten retrospective studies (123 patients) were analyzed.
- Nonoperative group (41 patients): 4.87% infection rate (2/41).
- Operative debridement group (82 patients): 2.33% infection rate (2/82).
Conclusions:
- Optimal management for pediatric type I open tibia fractures remains unclear.
- Selected low-energy injuries may be managed nonoperatively in the emergency department.
- Insufficient high-quality evidence to routinely deviate from current guidelines; consider energy absorption.
Aims:
The conventional management of the soft-tissue component of an open fracture involves emergent debridement. There is, however, evidence that questions this approach in the management of Gustilo-Anderson type I open fractures in paediatric patients. This systematic review aims to explore differences in infection rates between nonoperative management with antibiotics and operative debridement in children with type I open lower limb tibial fractures that do not require surgical fixation.
Methods:
A systematic review following the PRISMA guidelines was conducted. Patients aged under 18 years with Gustilo-Anderson type I open tibia fractures treated with either antibiotics alone or operative debridement were included. Polytrauma patients and those requiring operative fracture stabilization were excluded. Study bias was assessed with the ROBINS-I (Risk of Bias in Non-randomized Studies of Interventions) tool.
Results:
Ten retrospective studies of 123 patients with Gustilo-Anderson type I open tibial fractures were included. Nonoperative management in the emergency department with antibiotics was used in 41 patients, with two infections reported (4.87%). Operative debridement was performed in 82 patients, with two infections reported (2.33%).
Conclusion:
The optimum management for paediatric Gustilo-Anderson type I open tibia fractures remains unclear. There may be selected cases, with true low-energy injury without operative fixation requirements, which can be managed in the emergency department. However, there is not sufficient high-quality evidence to advocate for regular deviation from current guidelines in open tibia fractures in paediatric patients. Decision-making must take into account the energy absorbed, as this factor can be misleading within the current classification system.
More Related Videos
04:41Treatment with Locking Intramedullary Nailing for Intertrochanteric Fracture of the Femur Utilizing a New Awl with a Distal Positioner
Published on: June 6, 2025
07:35Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
Published on: April 11, 2012
Related Concept Videos
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the...
Combined Effects of Drugs: Synergism
Such synergistic combinations...
Acute Pyelonephritis II: Diagnostic Studies and Management
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Tonsillitis II: Management
Antimicrobial Effectiveness