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Pregnancy outcomes and vitiligo: protocol for a scoping review
Behnaz Esmaeili1, Mahin Afroushe1, Shahnaz Esmaeili2
1Department of Basic Medical Sciences, Khoy University of Medical Sciences, Khoy, Iran.
BMJ Open
|August 7, 2025
Summary
This review examines pregnancy outcomes in women with vitiligo, a skin condition. It synthesizes current research to clarify risks and inform clinical practice regarding vitiligo and pregnancy.
Area of Science:
- Dermatology
- Obstetrics
- Autoimmune Diseases
Background:
- Autoimmune diseases impact pregnancy, posing risks to mothers and fetuses.
- Vitiligo, a depigmentation disorder, has controversial associations with adverse pregnancy outcomes (APOs).
Purpose of the Study:
- To conduct a scoping review of existing literature on pregnancy outcomes in patients with vitiligo.
- To explore and summarize the current evidence regarding adverse pregnancy outcomes (APOs) in vitiligo patients.
Main Methods:
- A five-stage scoping review methodology (Arksey and O'Malley) will be employed.
- Literature searches will be conducted in PubMed and Scopus databases up to January 2025.
- Data extraction and charting will be performed by two reviewers, with results presented using tables and graphs.
Main Results:
- This section is to be populated upon study completion.
- The review will map the available evidence on pregnancy outcomes in vitiligo patients.
- Analysis will focus on identifying and exploring reported adverse pregnancy outcomes (APOs).
Conclusions:
- This scoping review will provide a comprehensive overview of pregnancy outcomes in vitiligo patients.
- Findings will help clarify the relationship between vitiligo and adverse pregnancy outcomes (APOs).
- Results will be disseminated through peer-reviewed publications.
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