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Food-allergic asthma in general practice.

M L Burr, A M Fehily, N C Stott

    Human Nutrition. Applied Nutrition
    |October 1, 1985
    PubMed
    Summary
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    Food allergy plays a role in adult asthma for at least 4% of patients. While some asthmatics have positive food allergy tests, challenge testing often fails to confirm specific food triggers.

    Area of Science:

    • Allergy and Immunology
    • Respiratory Medicine
    • Clinical Nutrition

    Background:

    • Asthma is a common respiratory condition with various potential triggers.
    • The role of food allergy in adult asthma remains a subject of investigation.
    • Identifying specific food triggers is crucial for effective asthma management.

    Purpose of the Study:

    • To evaluate the significance of food allergy in adult asthma patients.
    • To determine the prevalence of food-induced asthma in a general practice setting.
    • To assess the diagnostic accuracy of allergy testing for food triggers in asthma.

    Main Methods:

    • A case-control study comparing 72 asthmatics with 72 matched controls.
    • Diagnostic procedures included dietary elimination and challenge testing.

    Related Experiment Videos

  • Skin prick tests and food-specific IgE-RAST were performed.

    • Main Results:

    • Asthmatics showed higher rates of positive food allergy tests (skin prick, IgE-RAST) than controls, but specificity was limited.
    • Only one patient demonstrated clear clinical improvement after wheat elimination.
    • Most suspected food-induced asthma cases were not confirmed by challenge testing.

    Conclusions:

    • Food allergy may provoke asthma symptoms in at least 4% of adult asthmatics.
    • Standard allergy tests are not always reliable for identifying asthma-related food triggers.
    • Dietary challenge testing is essential for confirming food-induced asthma.