Mapping ICD-10 Codes for Oncology Diseases to OncoTree: Lessons Learned

Despite the existence of ICD-O for tumor classification, the broader ICD-10 system is often used in practice. While OncoTree is significant in research and molecular tumor boards, it provides a more detailed classification based on molecular and histological characteristics, crucial for clinical trial enrollment and data comparison. Therefore, a mapping between ICD-10 and OncoTree was developed. The mapping uses SNOMED CT as an intermediary step because both ICD-10 and OncoTree are structured differently. During the mapping process, some challenges arose, such as differences in the structure of the coding systems and inaccurate mappings. Despite this, the approach achieved an accuracy rate of 86.18%, which is considered satisfactory. Future efforts will focus on refining the mapping process to enhance its integration into production systems.