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Related Concept Videos

Diabetes Mellitus: Overview and Type I Subtype01:22

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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
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Diabetes: Symptoms, Diagnosis, and Complications01:15

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For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is...
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Diabetes Mellitus: Type 2 and Gestational01:22

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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
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Insulin is released by beta cells of the pancreas when blood glucose levels are high. It facilitates glucose absorption and utilization in insulin-dependent cells with insulin receptors on their plasma membranes. Insulin promotes glucose uptake by increasing the number of glucose transport proteins in the cell membrane, allowing glucose to enter the cell. As a result, glucose utilization and ATP production are enhanced.
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Updated: Sep 12, 2025

Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
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NEWS-Based Engine for Monitoring Adults Diabetic Patients.

Humberto F Mandirola Brieux1,2,3, Jakir Hossain Bhuiyan Masud4,3, Fernando La Rosa1

  • 1HL7 Argentina, Argentina.

Studies in Health Technology and Informatics
|August 8, 2025
PubMed
Summary
This summary is machine-generated.

A National Early Warning Score (NEWS) alert engine monitors diabetic patients remotely, enabling early detection of diabetic ketoacidosis and hypoglycemia. This system facilitates proactive interventions and improves patient outcomes through data-driven insights.

Keywords:
Diabetes Vital signHL7 FHIRNEWSREST APITelemedicine

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Area of Science:

  • Medical Informatics
  • Endocrinology
  • Patient Monitoring

Background:

  • Diabetic patients require continuous monitoring for early detection of complications.
  • Existing monitoring systems may not adequately predict clinical deterioration in diabetic patients.
  • National Early Warning Score (NEWS) is a validated tool for predicting clinical deterioration in pediatric patients.

Purpose of the Study:

  • To adapt and utilize a NEWS-based alert engine for remote monitoring of diabetic patients.
  • To identify early signs of deterioration and complications, such as diabetic ketoacidosis (DKA) and hypoglycemia.
  • To enable timely and personalized interventions based on individual risk scores.

Main Methods:

  • Implementation of an alert engine utilizing the NEWS scoring system.
  • Remote monitoring of diabetic patients' physiological parameters.
  • Adaptation of the NEWS scoring system for diabetic patient monitoring.

Main Results:

  • Early detection of warning signs for diabetic ketoacidosis (DKA) and hypoglycemic events.
  • Identification of patients at risk for clinical deterioration.
  • Facilitation of personalized interventions based on risk stratification.

Conclusions:

  • A NEWS-based alert engine enhances remote monitoring for diabetic patients.
  • Early detection of complications and timely interventions improve patient outcomes.
  • The system supports healthcare teams with data-driven insights for better treatment decisions.