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Updated: Sep 12, 2025

Developing Photosensitizer-Cobaloxime Hybrids for Solar-Driven H2 Production in Aqueous Aerobic Conditions
Published on: October 5, 2019
Photoinduced Cobaloxime Catalysis for Oxidant-Free Radical Cyclization of 2-Methylthiolated Alkynones to Access
Mengxu Zhong1, Fangyu Bian1, Miao-Miao Li1
1Division of Molecular Catalysis and Synthesis, Henan Institute of Advanced Technology, Zhengzhou University, Zhengzhou 450001, P. R. China.
Abstract:
An oxidant-free radical phosphinylation/cyclization of 2-methylthiolated phenylalkynones with secondary phosphine oxides by photoinduced cobaloxime catalysis is described. The reaction tolerates a wide range of substrates, particularly those that are sensitive to chemical oxidation, affording various phosphorylated thiochromones in good yields with methane evolution. The synthesis of new monophosphine and phosphine-olefin ligands as well as the construction of an iridium complex highlight the great potential applications of this approach. In addition, preliminary mechanistic studies were performed to elucidate the reaction mechanism.
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