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Analysis of the Diagnostic Value of Combined Urinary Dry Chemistry Analysis and Urinary Sediment Analysis for Urinary
Jinyang Li1, Yijia Liang1, Yanli Zou1
1Laboratory Department, The 964th Hospital, 130062 Changchun, Jilin, China.
Objective:
Urinary dry chemistry and urinary sediment microscopy have gradually become important auxiliary methods for the diagnosis of urinary tract infection (UTI). This study aimed to explore the application value of the combination of the two in diagnosing UTI.
Methods:
Patients with suspected UTI who were admitted to our hospital from October 2022 to October 2024 were retrospectively collected. All patients underwent urinary dry chemistry and urinary sediment microscopy. The number of red blood cells (RBCs), white blood cells (WBCs) and hyaline casts in the urine samples of the two groups was observed and compared. The diagnostic results of urine bacterial culture were used as the "unified standard" for diagnosis. The positive results of UTI in patients with two test methods and combined test method were compared. The sensitivity, specificity, accuracy, positive predictive value, negative predictive value and consistency analysis were compared.
Results:
A total of 622 patients were enrolled, and 601 patients were finally included. No significant difference was found in the indices of urine RBCs, WBCs and hyaline casts between the two test methods (p > 0.05). Amongst the 601 patients who underwent urine culture and urine examination, 390 cases were finally confirmed to have UTI by urine culture, with a positive rate of 64.89%. The positive rate of urinary dry chemistry was 88.97%, and the positive rate of urinary sediment microscopy was 83.33%. The positive rate of combined detection was 93.85%, which was high (p < 0.05). According to the results of urine bacterial culture, the sensitivity, accuracy, negative predictive value and positive predictive value of the combined test were significantly higher than those of the single application test (p < 0.05). The diagnostic results of the combined test were highly consistent with the results of urine bacterial culture (κ = 0.795, p < 0.001).
Conclusions:
Combined testing has a high value in diagnosing UTI. It can significantly improve the diagnostic efficiency of UTI.
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