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Updated: Sep 12, 2025

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
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Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer

Published on: June 9, 2023

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Pediatric Thyroid Cancer Multidisciplinary Team Improves Adherence of Radioactive Iodine Treatment According to

Shravan Gowrishankar1, Dylan Thompson1, Sara K Bartz2

  • 1Vanderbilt Department of Otolaryngology-Head and Neck Surgery, Nashville, Tennessee, USA.

Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
|August 8, 2025
PubMed

Insights

A multidisciplinary team (MDT) approach improved adherence to pediatric thyroid cancer guidelines. Fewer low-risk patients received radioactive iodine (RAI) therapy post-MDT, with more receiving recommended tests.

Area of Science:

  • Pediatric Endocrinology
  • Oncology
  • Surgical Oncology

Background:

  • Pediatric thyroid cancer management requires adherence to specific postoperative surveillance guidelines.
  • The 2015 American Thyroid Association (ATA) guidelines provide a framework for optimal patient care.
  • Evaluating adherence to these guidelines is crucial for improving outcomes in young patients.

Purpose of the Study:

  • To determine if a multidisciplinary team (MDT) approach enhances adherence to the 2015 ATA postoperative surveillance guidelines for pediatric thyroid cancer.
  • To compare guideline adherence before and after the implementation of an MDT.

Main Methods:

  • Retrospective review of pediatric patients with thyroidectomy for papillary or follicular thyroid cancer (2017-2024).
  • Comparison of two cohorts: pre-MDT (2017-2020) and post-MDT (2021-2024).
  • Analysis of postoperative thyroglobulin (Tg) tests, diagnostic iodine scans (I-123), radioactive iodine (I-131) administration, and endocrinologist involvement.

Main Results:

  • Fewer low-risk patients received radioactive iodine (I-131) therapy post-MDT (0% vs. 47%, P=.04).
  • Increased adherence to ATA guidelines for postoperative Tg tests and I-123 diagnostic scans was observed in the post-MDT period.
  • The introduction of the MDT correlated with improved guideline adherence.

Conclusions:

  • The MDT approach is associated with better adherence to the 2015 ATA guidelines in pediatric thyroid cancer patients.
  • Reduced utilization of I-131 in low-risk patients post-MDT suggests more precise application of guidelines.
  • The MDT model is vital for optimizing postoperative care and surveillance in this population.
Abstract

Keywords:
ATA 2015 guidelinesMDTRAImultidisciplinary teampediatricpediatric thyroid guidelinesradioactive iodinethyroid cancer

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