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SUMMER: A Practical Tool for Identifying Factors and Biomarkers Associated with Pan-cancer Survival
Junyi Xin1,2, Silu Chen2,3, Huiqin Li2,3
1Department of Bioinformatics, School of Biomedical Engineering and Informatics, Nanjing Medical University, Nanjing, Jiangsu, China.
Abstract:
The application of Mendelian randomization (MR) analytical framework based on genome-wide association study (GWAS) datasets has uncovered hundreds of risk factors involving disease development that included tumorigenesis, but the practice of MR in cancer survival remains limited. Here, we will provide abundant details of our previously established tool, SUrvival related cancer Multi-omics database via MEndelian Randomization (SUMMER; http://njmu-edu.cn:3838/SUMMER/ ), which would help users systematically evaluate the causal effects of risk factors and circulating biomarkers on pan-cancer survival.
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