Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tuberculous spondylitis in adults.

R M Lifeso, P Weaver, E H Harder

    The Journal of Bone and Joint Surgery. American Volume
    |December 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Case of Apoplexia Hydrocephalica.

    The Medical and physical journal·2018
    Same author

    Traffic accidents in Saudi Arabia: An epidemic.

    Annals of Saudi medicine·2010
    Same author

    Physical therapy management of lower extremity amputees.

    The Physiotherapy review·2010
    Same author

    Coexistence of two different intraspinal tumors. Case report and review of the literature.

    Neurosurgical focus·2006
    Same author

    Comparison of the ex vivo chemosensitivity of uveal and cutaneous melanoma.

    Melanoma research·2001
    Same author

    Vertical ground reaction forces: objective measures of gait following hip arthroplasty.

    Gait & posture·2001

    Spinal tuberculosis diagnosis can be challenging, but surgical decompression offers rapid neurological recovery. Adequate chemotherapy prevents disease progression and reactivation.

    Area of Science:

    • Infectious Diseases
    • Neurosurgery
    • Orthopedic Surgery

    Background:

    • Spinal tuberculosis (Pott's disease) presents diagnostic challenges, with imaging and skin tests often yielding false negatives.
    • Neurological impairment and spinal instability are significant complications requiring timely intervention.
    • Tuberculomas and tuberculous arachnoiditis can occur even without apparent bone lesions.

    Purpose of the Study:

    • To evaluate the diagnostic difficulties in spinal tuberculosis.
    • To assess the efficacy of surgical versus non-surgical management for neurological recovery.
    • To determine the optimal surgical approach and outcomes in spinal tuberculosis.

    Main Methods:

    • Retrospective analysis of 107 adult patients with spinal tuberculosis.

    Related Experiment Videos

  • Evaluation of diagnostic modalities including bone scans, gallium scans, and tuberculin skin tests.
  • Comparison of outcomes for anterior decompression and fusion, laminectomy, and non-surgical treatment.

    • Main Results:

    • Diagnostic tests showed low sensitivity: bone scans (35% negative), gallium scans (70% negative), tuberculin skin tests (14% negative).
    • Anterior decompression and fusion was the preferred surgical procedure for 53 patients.
    • Neurological recovery was highest after anterior decompression (94%), followed by non-surgical treatment (79%) and laminectomy (55%).
    • Surgically treated patients experienced faster neurological recovery and pain relief. No kyphosis progression was observed.
    • Adequate chemotherapy (isoniazid, rifampin, ethambutol) resulted in no resistant organisms, disease progression, or reactivation at 12 months.

    Conclusions:

    • Spinal tuberculosis diagnosis requires a high index of suspicion due to limitations of conventional tests.
    • Anterior decompression and fusion is an effective surgical option for spinal tuberculosis, leading to rapid neurological recovery.
    • Comprehensive chemotherapy is crucial for managing spinal tuberculosis and preventing recurrence.