Related Experiment Video
Updated: Sep 12, 2025
Endobronchial Ultrasound-guided Intratumoral Injection of Cisplatin for the Treatment of Isolated Mediastinal Recurrence of Lung Cancer
Published on: February 12, 2017
Durable Complete Response to Pembrolizumab in MSI-H Advanced Pancreatic Cancer
Background:
Pancreatic ductal adenocarcinoma remains a highly aggressive cancer with limited treatment options and poor prognosis. Pembrolizumab has shown potential in patients with micro satellite instability-high tumors. We report a rare case of complete remission of metastatic pancreatic cancer.
Methods:
A 58-year-old male with MSI-H advanced PDAC, who progressed during adjuvant and metastatic first-line treatment, was treated with pembrolizumab showed significant clinical improvement.
Results:
Pembrolizumab led to complete response. At the time of the report, the patient had durable response of 13 months.
Conclusions:
This case demonstrates the promising role of pembrolizumab in MSI-H advanced pancreatic cancer.
