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Target-Mediated Drug Disposition Revisited: Michaelis-Menten Approximations for Bivalent Drug Molecules

Ronny Straube1

  • 1Pioneering Medicines, Cambridge, Massachusetts, USA.

CPT: Pharmacometrics & Systems Pharmacology
|August 8, 2025
PubMed

Keywords:
avidityirreversible binding constantmonoclonal antibodynonlinear PK

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