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Related Concept Videos

Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

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Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
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Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

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Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
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Aneurysm I: Introduction01:30

Aneurysm I: Introduction

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An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
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Aortic Regurgitation I: Introduction01:15

Aortic Regurgitation I: Introduction

36
IntroductionAortic regurgitation is characterized by the backward flow of blood from the aorta into the left ventricle during diastole and arises from the improper closure of the aortic valve. This condition results in left ventricular volume overload and can stem from both acute and chronic etiologies, each contributing uniquely to the disease's progression and symptomatology.Acute and Chronic CausesAcute aortic regurgitation often results from events that suddenly impair the integrity of the...
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Aortic Regurgitation II: Clinical Features and Diagnostic Tests01:22

Aortic Regurgitation II: Clinical Features and Diagnostic Tests

52
Aortic valve regurgitation (AR) occurs when the aortic valve fails to close properly, allowing blood to flow backward from the aorta into the left ventricle. This backflow can result in two distinct clinical presentations: acute and chronic AR, each characterized by its own set of symptoms and physical findings.Acute Aortic RegurgitationAcute AR presents with a sudden onset of severe symptoms. Patients typically experience profound dyspnea (shortness of breath), chest pain, and signs of left...
52
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

23
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
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Updated: Sep 12, 2025

Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
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Late Chronic Left Ventricular Pseudoaneurysm Thrombosis.

Jacopo Lin1, Matteo Saccocci2, Eren Cetinel1

  • 1School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.

JACC. Case Reports
|August 8, 2025
PubMed
Summary

Left ventricular pseudoaneurysm (LVPA), a rare complication after myocardial infarction, carries a high risk of rupture and thrombus. Early diagnosis and intervention, surgical or percutaneous, are crucial for patient outcomes.

Keywords:
cardiovascular diseasechronic heart failureleft ventriclemyocardial infarctionthrombosisthrombustreatment

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Area of Science:

  • Cardiology
  • Cardiovascular Surgery
  • Medical Imaging

Background:

  • Left ventricular pseudoaneurysm (LVPA) is a rare but life-threatening complication following myocardial infarction.
  • LVPA can lead to significant complications such as thrombus formation and hemodynamic instability.

Observation:

  • This report details two cases of LVPA presenting years after myocardial infarction.
  • One patient had a large apical LVPA treated surgically, while the other had a posterolateral LVPA managed percutaneously.

Findings:

  • Diagnosis was confirmed using echocardiography and cardiac computed tomography.
  • Both cases highlighted the potential for delayed presentation of LVPA.

Implications:

  • Early recognition and prompt intervention, surgical or percutaneous, are critical for managing LVPA.
  • These distinct therapeutic approaches underscore the importance of tailored treatment strategies for LVPA.